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Active pharmaceutical ingredient is referred as the substance intended for the furnishing of the pharmacological activity or to have a direct effect on the diagnosis, cure, mitigation, prevention or treatment of the disease or also have a direct effect in restoring, correcting, modifying physiological functions in the patients. Antibiotics are the drugs used to treat infections caused by the germs or parasites by inhibiting one of the mechanisms in their body or destroying them. These drugs are used only in the cases of the bacterial or the parasitic infections. Some of the major subclasses of the antibiotics active pharmaceutical ingredients are penicillin, cephalosporins, carbapenems, macrolides, aminoglycosides, quinolones, sulfonamides, tetracyclines, and so on. This class covers the total of 28% of the antibiotic drugs. The second largest class of the antibiotics after the cephalosporins in the terms of the sales is the broad spectrum penicillin. This class covers total of 19% of the antibiotic drugs. The third largest class of the antibiotics is the fluoroquinolones. As per the Antibiotics Pharmaceutical conferences, this class covers 17% of the antibiotic drugs sales. Some examples of the antibiotic drugs are fluoroquinolones, linezolid, trimethoprim-sulfamethoxazole, metronidazole and much more.
COVID-19 Scenario Analysis:
Pharmaceutical and biotech companies together with governments around the globe are working to address the COVID-19 outbreak, from supporting the development of vaccines to planning for medicines supply chain challenges. Currently, around 115 vaccine candidates and 155 molecules are in the R&D pipeline. Moreover, commonly used drugs such as Hydroxychloroquine have witnessed dramatic surge in demand for the management of COVID-19. Such high demand for these drugs has presented huge opportunity for manufacturers of COVID-19 management drugs, as many developed countries had shortage of these drugs. Owing to the demand for vaccine and treatment drugs for COVID-19, the pharmaceutical and biotechnology industry is expected to witness a significant growth in the future
Rise in prevalence of infectious diseases like bacterial infections can fuel the growth of the market, increase in the number of patients of the infectious diseases can surge the usage of the antibiotic drugs and thus, boost the growth of the market. Rise in the healthcare expenditure is proving to be of great help in the growth of the market. Furthermore, increasing approvals for the generic drugs in the market can also fuel the growth of the market. Moreover, rise in R&D activities of the advanced molecules of the drug entities can increase the revenue of the antibiotic API manufacturers, which in turn fuels the growth of the antibiotic active pharmaceutical ingredient market.
However, high cost of the drug development and lack of awareness of the about utilization of the drugs and the side effects related to usage of the drugs are expected to hamper the growth of the market.
In March 2018, the announcement of the launch of generic version of the drug called doxycycline monohydrate immediate release capsules in the dose 50 mg, 75 mg, 100 mg was made by Mayne Pharma Group Limited.
In February 2021, the Glenmark Pharmaceuticals Limited announced the launch of the SUTIB oral capsule in the dose 12.5 mg, 25 mg, 50 mg. This is the oral multi-kinase inhibitor that works against the kidney cancer.
The increase in the incidence of infectious diseases and new innovations in the drug entity can help to increase the usage of the antibiotic drugs. Moreover, rise in spread of awareness regarding utilization of the drugs may also help to surge the usage of antibiotic API.
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