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Humanized mouse is a mouse that possesses functioning human genes, cells, tissues, and/or organs in case of biological and medical research for human therapeutics. These mouse models are used to model the human immune system in scenarios of health and pathology.
Usage of mouse models for identification of immunodeficiency disorders, cancers, and other rare diseases, increase in R&D activities carried out by pharmaceutical & biotechnology companies; continuous support & initiatives from governments & private sectors for research on mouse models; and growth in adoption of modified medicine increase the demand for personalized mouse models.
However, stringent regulations and laws formulated for ethical use of animals and costly procedures for maintenance of animal housing restrain the growth of the global humanized mouse model market. Increased production of monoclonal antibodies and improvement of healthcare in developing nations are expected to provide growth opportunities for the market.
The humanized mouse model is segmented on the basis of type, application, end user, and region. Based on type, the market is bifurcated into cell-based humanized mouse model and genetic humanized mouse model. Cell-based humanized mouse models segment is further classified into CD34, PBMC, and BLT. Applications covered in the study include immunology & infectious diseases, neuroscience, oncology, hematopoiesis, toxicology, and others.
By end user, the market is divided into contract research organizations (CROs), pharmaceutical & biotechnology companies, and academic & research institutes. Geographically, it is analyzed across North America (U.S., Canada, and Mexico), Europe (Germany, France, UK, Italy, Spain, and rest of Europe), Asia-Pacific (Japan, China, India, Australia, South Korea, and rest of Asia-Pacific), and LAMEA (Brazil, Saudi Arabia, South Africa, and rest of LAMEA).
Key players operating in the global humanized mouse model market include The Jackson Laboratory, Taconic Biosciences, Inc., Harbour BioMed, HuMurine Technologies, Inc., Vitalstar Biotechnology Co. Ltd., Crown Bioscience, Inc., ingenious targeting laboratory, Axenis S.A.S., TRANS GENIC, Inc., and genOway S. A.
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