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The human lung is a very delicate organ that functions as an entry and exit of the exchange of gases. Hence, the process of aerosolized materials entry concerning the lung cells is a very well focused and researched field of human health. Disorders in lung diseases affect the function and structure of the lung can cause lethal effects. Generally, animal models are used for the lung disorder analysis and the development of the lung diseases. On the contrary, animal models are not fully to replicate the human lung disease and the development processes, or spotlighting an area of the lung complements with the human to understand the pathological mechanism and the developments.
Although there have been many negative effects, animal testing is very prevalent and used for the study of various diseases, risk assessment, and new drug development. In-vitro lung model are made by macrophages culturing, dendritic cells favorable medium culture, and epithelial cells.
Pharmaceutical and biotech companies together with governments around the globe are working to address the COVID-19 outbreak, from supporting the development of vaccines to planning for medicines supply chain challenges. Currently, around 115 vaccine candidates and 155 molecules are in the R&D pipeline. Moreover, commonly used drugs such as Hydroxychloroquine have witnessed a dramatic surge in demand for the management of COVID-19. Such high demand for these drugs has presented huge opportunities for manufacturers of COVID-19 management drugs, as many developed countries are short of these drugs. Owing to the demand for vaccine and treatment drugs for COVID-19, the pharmaceutical and biotechnology industry is expected to witness a significant growth in the future.
Owing to such factors, COVID 19 is expected to have a significant impact on the In Vitro Lung Model market.
The focus has been shifting from animal testing models to finding out new alternatives, upgrades in the technology of cell culture, along with the development of new 3D in vitro models, are favoring the factors of the in-vitro lung model market.
Additionally, investments and funding for the development of product and research purposes, advancements in 3D cell culture technology, innovative technology in the 3D in vitro models are some of the other factors propelling the growth of the in vitro lung model market.
On the other hand, the scarcity of skilled professionals like technicians and researchers needed for setting up the experiments and their processes which includes complex in vitro models is the biggest challenge faced in the in vitro lung model market.
On June 13th, 2018, InSphero AG, announced that they have received USD 10 million for their research on discovery platforms for cancer and metabolic diseases. InSphero AG is an innovator and a provider of 3D cell-based platforms in efficacy testing and drug discovery.
On September 26th, 2018, The US patent office received a patent for their lung-on-chip system, AlveoliX which will be assisting in drug candidates development for diseases related to the lungs.
Biotechnology and Pharmaceutical companies, Contract research organizations, and academic and government research institutes are the major consumers of the in-vitro lug model market. Amongst them, the life-science companies are the biggest end-users of the market.
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