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Nucleic acid sample preparation involves a range of techniques to transform a sample, which cannot be directly analyzed into one that fits the requirements of the analytical technique to be used, such as reverse transcription (RT) or PCR. Nucleic acid sample purification and quality assessment are important steps in experimental workflows since the quality of nucleic acids will affect the performance in downstream reactions. When working with cells or tissues as the starting material, the first step of the nucleic acid purification process is cell lysis or membrane permeabilization. This process breaks open the cell membranes and disrupts the cellular structure to create a cell lysate. This allows the nucleic acid of interest to be accessed and separated away from unwanted cellular components
COVID-19 scenario analysis:
The main healthcare industries such as Pharmaceutical and biotech companies joined their hands with governments around the globe and are working to manage the COVID-19 outbreak. This is done by supporting the development of vaccines to planning for medicines supply chain challenges. There is continuous research going on regarding the development of vaccines for the management of the disease. There are around 115 vaccine candidates and 155 molecules are in the R&D pipeline. The commonly used drugs such as Hydroxychloroquine have seen dramatic surge in demand for the management of COVID-19. This high demand for these drugs has presented bigger opportunity for manufacturers of COVID-19 management drugs, as many developed countries are short of these drugs. The demand for vaccine and treatment drugs for COVID-19, the pharmaceutical and biotechnology industry is anticipated to witness a significant growth in the coming years.
The major factor affecting the Nucleic Acid Isolation and Purification market includes the increase in the technological advancements for the isolation and purification of nucleic acid, would help the market grow in the forecast period. Furthermore, the rise in R&D for the extraction of nucleic acid would propel the industry to grow. The surge in the automation of the procedure would boost the industry in the near future. However, the higher cost of the automated system may impede the market growth.
In June 2020, Omega Bio-tek, Inc. announced the launch of the Mag-Bind Viral RNA Xpress Kit for the rapid and reliable isolation of Viral RNA from nasopharyngeal (NP) swab specimens that are dry or in viral transport media (VTM). The new kit aims to combat the shortage of RNA purification kits, which is used in the first steps of COVID-19 testing. The new magnetic bead-based extraction kit is adaptable to most liquid handling platforms for scalable, high-throughput purification.
In January 2018, Beckman Coulter Life Sciences launched a family of FormaPure reagent kits for extracting nucleic acid from often challenging formalin-fixed, paraffin-embedded (FFPE) tissues. FormaPure reagent kits represent a single chemistry system designed and optimized for use in next-generation sequencing (NGS) and other downstream applications, including qPCR/ddPCR/PCR.
In January 2017, Takara Bio USA Holdings, Inc. ("TBUSH") announced that it has completed the acquisition of Rubicon Genomics, Inc. ("Rubicon"). The Takara Bio Group provides a wide range of life science products and services under the Takara, Clontech, and Cellartis brands that assist discovery, translational and clinical scientists in the advancement of their work.
The Rubicon acquisition will allow the Takara Bio Group to augment and expand its worldwide commercial offerings in next generation sequencing (NGS) sample preparation and expand into new Nucleic Acid Isolation and Purification market. The acquisition will helps in gaining maximum attention of the healthcare professionals and hence would boost the growth in the near future.
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