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Sarcoidosis is an inflammatory disease in which clumps of inflammatory cells form in various organs called granulomas. These granulomas may cause organ inflammation. This disease is triggered by the body’s immune response to foreign particles such as bacteria, viruses, or chemicals. For some patients, sarcoidosis is a chronic condition and it may lead to the deterioration of the affected organ. Rarely, this disease can be fatal. Death usually is the result of complications with organs such as the heart, lungs, or brain. Drugs used in sarcoidosis include methotrexate and azathioprine, which can reduce inflammation by suppressing the immune system. Drugs such as hydroxychloroquine may help for elevated blood calcium levels.
COVID-19 Impact Analysis
COVID-19 is an infectious disease that originated in the Hubei province of the Wuhan city in China in late December. The highly contagious disease, caused by a virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is transmitted from human to human. Since the outbreak in December 2019, the disease has spread to almost 213 countries around the globe with the World Health Organization declaring it a public health emergency on March 11, 2020.
Pharmaceutical and biotech companies together with governments around the globe are working to address the COVID-19 outbreak, from supporting the development of vaccines to planning for medicine supply chain challenges. Currently, around 115 vaccine candidates and 155 molecules are in the R&D pipeline. Moreover, commonly used drugs such as hydroxychloroquine have witnessed a dramatic surge in demand for the management of COVID-19. Such high demand for these drugs has presented huge opportunities for manufacturers of COVID-19 management drugs, as many developed countries are facing a shortage of these drugs. Thus, the pharmaceutical and biotechnology industry industries are expected to witness significant growth in the future, owing to the demand for vaccines and treatment drugs for COVID-19. This, in turn, is expected to have a significant impact on the sarcoidosis drugs market.
Increase in awareness regarding the health of patients suffering from sarcoidosis is driving the growth of the market. In addition, surge in prevalence of sarcoidosis is influencing the market positively.
Extensive research undertaking and funding have been witnessed to control the rising prevalence of this disease, which is another factor that drives the sarcoidosis drug market growth.
Advancements in the healthcare industry along with rise in per capita income in the emerging markets such as Canada and the U.S. is accelerating the sarcoidosis drugs market growth.
However, sarcoidosis drugs available in the market have many side effects. Effective treatment for sarcoidosis is either unaffordable or unavailable. In addition, lack of awareness about the disease among physicians and patients in developing nations hinders the market growth of sarcoidosis drugs.
Foreign substances such as viruses and bacteria or chemicals may trigger the immune system. If the exposure to these substances is high, it may trigger sarcoidosis in a patient's body. With rise in pollution all over the world and increase in cases of new pathogens, there has been surge in the number of sarcoidosis cases.
Key players in the sarcoidosis drugs market are focusing on new drug developments, product launches, and mergers & acquisitions with smaller players.
In December 2018, aTyr Pharma, Inc. announced its drug ATYR1923 to be under phase 1b/2 of clinical trials. This drug is meant for the treatment of pulmonary sarcoidosis. It can help improve care for sarcoidosis patients, as it is designed for offering better tolerability and immunogenicity in such patients.
In July 2016, AbbVie, Inc. received approval for its drug Humira (adalimumab). This drug is efficient in minimizing sarcoidosis symptoms by decreasing the levels of tumor necrosis factor (TNF). It can further reduce swelling of the lymph nodes that are seen in sarcoidosis. Humira is injected subcutaneously and can be used as an alternative for people who cannot tolerate other sarcoidosis treatments, which may include the use of drugs such as prednisone and prednisolone (corticosteroids).
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Questions Answered in the Global Sarcoidosis Drugs Market Report
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