Tangential flow filtration (TFF) is a rapid and efficient method for separation and purification of biomolecules. It can be applied to a wide range of biological fields such as immunology, molecular biology, biochemistry, and microbiology. It can be used to concentrate and desalt sample solutions ranging in volume from 10 mL to thousands of liters. It can be used to fractionate large from small biomolecules, harvest cell suspensions, and clarify fermentation broths and cell lysates.
The growth of the global tangential flow filtration market can be assigned to the growth in the biopharmaceutical sector, rising funding by pharmaceutical companies, the increasing adoption of single-use technologies, and the benefits associated with tangential flow filtration. The efficient applications of tangential filtration technique are for various purposes, such as downstream processing in bio-manufacturing, separation and purification of biomolecules, and upstream harvesting.
COVID-19 scenario analysis:
Pharmaceutical and biotech companies together with governments around the globe are working to address the COVID-19 outbreak, from supporting the development of vaccines to planning for medicines supply chain challenges. Currently, around 115 vaccine candidates and 155 molecules are in the R&D pipeline. Moreover, commonly used drugs such as Hydroxychloroquine have witnessed dramatic surge in demand for the management of COVID-19. Such high demand for these drugs has presented huge opportunity for manufacturers of COVID-19 management drugs, as many developed countries are short of these drugs. Owing to the demand for vaccine and treatment drugs for COVID-19, the pharmaceutical and biotechnology industry is expected to witness a significant growth in the future. Considering these factors, COVID- 19 is expected to have significant impact on Tangential Flow Filtration Market.
Applications of tangential flow filtration
- The primary applications for Tangential Flow Filtration are concentration, filtration and bifurcation of large from small biomolecules. In addition, it is also used fortransfer of cells and also cellular waste from fermentation or cell culture broths.
- Tangential flow filtration is used for bifurcation of the virus particles. In Human influenza A virus, its particles are spherical with an average size of 100 nm. Use of a 0.1 micro membrane leads to transit of virus particles less than 100 nanometer into the permeate and an increase of larger particles in the permeation.
GROWTH FACTORS:
- In 2018, North America contributed for the increased share of the global market of Tangential Flow Filtration market, followed by Europe. Factors like strong presence of Tangential Flow Filtration product manufacturers in the region also established biopharmaceutical industry, notable growth in R&D spending by pharmaceutical and biotechnology companies, and the presence of intellectual property system for innovation of biologics production are boosting the growth of the Tangential Flow Filtration market in North America.
- There was anincrease in the acceptance of single-use technologies whichcredited to the benefits associated with them. Factors such as reduced cross-contamination, increased flexibility, and decreased process timewere responsible for the growth. These fully automated single-use systems of tangential flow has diverse advantages like reduced validation, lower capital costs, and reduced cleaning requirements. Additionally, with increasing technological advancements in single-use Tangential Flow Filtration, the biologics manufacturing is expected to reshape and contribute to the growth of the tangential flow filtration market.
Key benefits of the report:
- This study presents analytical depiction of global tangential flow filtration industry along with the current trends and future estimations to determine the investments to be made.
- The report presents information related to key drivers, restraints and opportunities with detailed analysis of tangential flow filtration market share.
- The current market is quantitatively analyzed from 2019-2027 to highlight the tangential flow filtration market growth scenario.
- Porter’s five forces analysis gives the potency of buyers and suppliers in the market.
- The report provides a detailed global tangential flow filtration market analysis based on competitive intensity what will be the scenario in upcoming years.
Questions answered in the Sterile Filtration Market research report:
- Who are the leading market players active in the tangential flow filtration market?
- What are the current trends that will influence the market in the next upcoming years?
- What are the driving factors, opportunities and restraints in the tangential flow filtration market?
- What will be the forecast for the future that would help in taking further strategic steps?
Key Market Segments
- By Type
- Membrane Filters
- Cassettes
- Capsules & Cartridges
- Reusable Tangential Flow Filtration System
- Single use Tangential Flow Filtration System
- Automated Systems
- Filtration Accessories
- By Technology
- Microfiltration
- Ultrafiltration
- Reverse Osmosis
- Nano Filtration
- By Application
- Viral Vector and Vaccine Purification
- Other Applications (Drug Formulation, Blood Plasma Fractionation, Media and Buffer Preparation, and Pharmaceutical Water Purification
- Bioprocess Applications:
- Upstream Processing
- Downstream Processing
- By Region
- North America
- Europe
- Germany
- France
- UK
- Spain
- Italy
- rest of Europe
- Asia-Pacific
- China
- India
- Japan
- Australia
- rest of Asia-Pacific
- LAMEA
- Brazil
- South Africa
- Saudi Arabia
- rest of LAMEA
Key Market Players
- GE Healthcare
- Danahar Corporation
- Sartorius AG
- Merck KgaA
- Novasep
