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A15455 | Pages: 211 | Charts: 54 | Tables: 100 |
The global wilson disease drugs market size was valued at $595.2 million in 2021, and is projected to reach $848.2 million by 2031, growing at a CAGR of 3.6% from 2022 to 2031. Wilson’s disease (WD) is an inherited disorder in which defective biliary excretion of copper leads to its accumulation, particularly in the liver and brain. The disease is progressive and, if left untreated, may cause liver (hepatic) disease, central nervous system dysfunction, and death. Early diagnosis and treatment may prevent serious long-term disability and life-threatening complications. The features of this condition include a combination of liver disease and neurological and psychiatric problems.
Affected people often experience a variety of neurologic (central nervous system-related) signs and symptoms, as well. Neurologic features often develop after the liver has retained a significant amount of copper; however, they have been seen in people with little to no liver damage. These symptoms may include tremors, muscle stiffness, and problems with speech, swallowing, and/or physical coordination. Almost all people with neurologic symptoms have Keyser–Fleisher rings – a rusty brown ring around the cornea of the eye that can best be viewed using an ophthalmologist’s slit lamp.
Treatment for Wilson’s disease is life-long and aimed at lowering copper levels to nontoxic levels, and at preventing the progression of the disease, and trying to reverse any signs and symptoms that have appeared because of copper accumulation in the body. Treatment may be divided into three parts: first treatment of symptomatic patients; second, maintenance therapy after the copper has been reduced in affected tissues; and third, in asymptomatic patients, maintenance therapy may be used from the beginning.
The several promising novel therapies, including chelators targeting specific cell types and cell-based and gene therapies, may revolutionize the care for WD patients. However, timely clinical diagnosis remains the main challenge, and many unmet needs exist because of possible clinical deterioration in treated patients.
Increase in demand for Wilson disease drugs market size is anticipated to increase globally during the forecast period, owing to increase in the prevalence of Wilson disease, advancement in R&D activities for drug development, and rise in adoption of early diagnosis. In addition, the increase in investment by players in R&D and presence of robust pipeline candidates, rise in expenditure on the development of healthcare infrastructure, increase in public awareness about the disease prevention in developing regions further drive Wilson disease drugs market growth. However, lack of awareness and diagnosis facility associated with Wilson disease treatment and high treatment cost due to complications restrain the wilson disease drugs industry growth. Conversely, high investment by the government for drug development and increase in healthcare expenditure are expected to offer lucrative wilson disease drugs market opportunity opportunities for the key player in the market.
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The Wilson disease drugs market is segmented on the basis of drug type, distribution channel and region. On the basis of drug type, the market is bifurcated into Penicillamine, Trientine and Zinc. On the distribution channel, the market is classified into hospital pharmacy, retail pharmacy, and online pharmacy. Furthermore, on the basis of region, the market is analyzed across North America, Europe, Asia-Pacific, and LAMEA.
Global Wilson disease drugs market by drug type
By drug type, the Wilson disease drugs market is divided into Penicillamine, Trientine and Zinc. The Penicillamine segment was the major revenue contributor of wilson disease drugs market share in 2021, and is anticipated to continue this trend during the forecast period, owing to increase in Wilson disease incidence and the pharmaceutical industry and research organizations have been forced to concentrate on the discovery of a treatment for Wilson disease. In addition, key players' ongoing research initiatives and the deployment of innovative technology in this market as well as significant government and private sector funding in the Wilson disease research which further boost the market growth. On the other side, Trientine segment is projected to exhibit the fastest market growth during the forecast period, owing to the Increase in approval of Wilson’s disease treatment drugs by regulatory authority. In addition, increase in healthcare expenditure and government support and initiatives taken by the countries to work on R&D activities for Wilson disease drugs development which further boost growth of wilson disease drugs industry.
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Global Wilson disease drugs market by distribution channel
By distribution channel, the market is divided into hospital pharmacy, retail pharmacy, and online pharmacy. The retail pharmacy segment was the major revenue contributor of wilson disease drugs market share 2021, and is anticipated to continue this trend during the wilson disease drugs market forecast , owing to increase in Wilson disease patients, the growing number of independent pharmacies and chains along with the availability of medications in supermarkets & mass retailers Furthermore, the rapid adoption of automation technologies, such as pharmacy robots, dispensing, and packaging systems is driving the segment growth.
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Global Wilson disease drugs market by region
By region, the Wilson disease drugs market is analyzed across North America, Asia-Pacific, Europe, and LAMEA. North America dominated the market in 2021, accounting for the highest share, and is anticipated to maintain this trend during the forecast period. Owing to investments made by the key players for various R&D activities as well as launch of new products in the U.S. In addition, increase awareness among the consumers for the adoption of Wilson disease drugs further boost the market growth.
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The major companies profiled in the report include ANI Pharmaceuticals, Inc., APOTEX, Bausch Health Companies Inc., Breckenridge Pharmaceutical, Inc., Dr. Reddy's Laboratories Ltd, Lupin Limited, NAVINTA LLC, Pfizer Inc., Teva Pharmaceutical Industries Ltd., Vivet Therapeutics.
Key Market Segments
Key Market Players