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Assays are used for the measurement for cellular proliferation, cytotoxicity, and cell viability and also are used commonly for monitoring the reaction and condition of cells in the culture after various treatments are been run on them. The decision of using the right assay for the completely depends on the amount of cells and their type which helps in the final and expected outcome. Cell proliferation assays help in keeping a track on the amount of cells,cellular divisions’ numbers, activity of the metabolism, or for DNA synthesis. Counting of the cells by the useof viability dyes like Calcein-AM or trypan blue provides both the proliferation speedalong with the viable cells percentage.
There are various methods used in the cell viability assay process:
There are also various other alternative methods and indirect methods for performing a cell viability assay measure like measuring cytotoxicity which involves counting down the number of dead or damaged cells. In some cases, apoptosis assay is used to assess cell viability.
Pharmaceutical and biotech companies together with governments around the globe are working to address the COVID-19 outbreak, from supporting the development of vaccines to planning for medicines supply chain challenges. Currently, around 115 vaccine candidates and 155 molecules are in the R&D pipeline. Moreover, commonly used drugs such as Hydroxychloroquine have witnessed a dramatic surge in demand for the management of COVID-19. Such high demand for these drugs has presented huge opportunities for manufacturers of COVID-19 management drugs, as many developed countries are short of these drugs. Owing to the demand for vaccine and treatment drugs for COVID-19, the pharmaceutical and biotechnology industry is expected to witness a significant growth in the future.
Owing to such factors, COVID 19 is expected to have a significant impact on the Cell Viability Assays market.
Funds for research increasing by the manufacturers, increasing demand for the cell-based assays in the research process, and focus on the development of cell-based therapeutics is increasing and thus affecting and boosting the growth of the cell viability assay market.
Growing frequency and incidences of chronic and infectious diseases are increasing the demand for cell viability assays market. Moreover, chronic disorders cases are increasing significantly due to lifestyle changes and the geriatric population. Heart-related disorderand cancer cases are leading to the growth of death rates, reasons for these diseases being change in lifestyles, increasing cases of obesity levels, urbanization,tobacco availability easily and broadly, and frequent diet alterations. As chronic disordersare at a rise, there is a huge demand concerning assays which are helping in the faster treatment and timelydetection of the patients’ condition.
However, the assays consume a lot of time to examinethe cell viability; its incubation period is around 4 hours. The absorbance process for the detection which is predominantly used in various assays is not as effective as compared to fluorescent and luminescent methods for the detection of theviability of cells. Hence, the viability of the cell is gettingaffected and also damages the cells till the experiment is completed. These factors are impacting the growth of the cell viability assay market negatively.
On April 1st, 2020, Biotek introduced a new cell count &viability starter kit which calautomaticallydo the process of cell counting and viability measurements in a mammalian cell suspension.
Pharmaceutical and biotechnology companies are the major consumers of the cell viability assays and are expected to grow even further in the coming years. This is possible due to the increasing number of R&D activities he companies are performing which is also helping in the development of biopharmaceutical products. Along with this, hospital and diagnostic laboratories are the major end-users for the cell viability assays.
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