According to a new report published by Allied Market Research, titled, “Chromatography Market by Type, Product, and End-User: Global Opportunity Analysis and Industry Forecast, 2021–2030," the global chromatography market size was valued at $8.70 billion in 2020 and is projected to reach $15.33 billion by 2030 registering a CAGR of 5.80% from 2021 to 2030.
Chromatography is essentially a physical method of separation in which the components of a mixture are separated by their distribution between two phases. One of these phases in the form of a porous bed, bulk liquid, layer or film is generally immobile (stationary phase) while the other is a fluid (mobile phase) that percolates through or over the stationary phase. Different components of the mixture travel through the stationary phase at different speeds, causing them to separate from one another. The nature of the specific mobile and stationary phases determines which substances travel more quickly or slowly and how they are separated. There are two types of chromatography include process chromatography, and preparative chromatography. Process scale chromatography is a scalable GMP manufacturing technique for the separation of biomolecules from a feedstock or slurry to produce bio therapeutics. This purification technique can be used in a variety of applications from gene therapies to biosimilars and bio-betters to vaccines and more. It is a cost-effective and efficient purification solution that enables high purity and high yield of the target molecule under optimal conditions. Preparative chromatography refers to the process of using HPLC to isolate material from an injected sample. It is the best generic method for the purification of small drugs and valuable chemical components at <10kg.
Increase in applications of chromatography in various fields such as pharmaceutical industries, chemical, and food industry, environmental testing laboratories, forensic science as well as growth in adoption of chromatography techniques in drug discovery process are principle driving factors, which boost the growth of the chromatography market. In addition, growth in popularity of hyphenated chromatography techniques LC-MS, GC-MS, LC-NMR, and LC-FTIR further fuel growth of the market. However, high cost of chromatography equipment, and shortage of skilled professionals to operate chromatography instruments, are some key challenges that hinder the growth of the market. In addition, presence of alternative technologies to chromatography such as precipitation, high-resolution ultrafiltration, crystallization, high-pressure refolding, charged ultra-filtration membranes, protein crystallization, capillary electrophoresis, aqueous two-phase extraction, three-phase partitioning, monoliths, and membrane chromatography also hamper the growth of the market. On the contrary, advancement in gas chromatography columns for petrochemical applications, and adoption of chromatography in R&D in cancer creates an opportunity for the manufacturers to tap and capitalize on the market.
COVID-19 is a large family of viruses that causes illness ranging from common cold to more severe respiratory diseases. The COVID-19 pandemic has helped the industry grow significantly, as the chromatography technologies employed by researchers as the scientific community strives to understand the Sars-CoV-2 virus and develop better therapies, vaccines, and diagnostic tools to aid in the fight against the Covid-19 pandemic. This supports the chromatography market to gain traction during the forecast period.
The chromatography market is segmented on the basis of type, product, end user, and region. By type, it is segmented into liquid chromatography, gas chromatography, thin-layer chromatography, and others include column chromatography, supercritical fluid chromatography systems, and paper chromatography. Liquid chromatography further classified into high-pressure liquid chromatography, ultra-pressure liquid chromatography, flash chromatography, and others include medium-pressure liquid chromatography systems, ion-exchange chromatography, partition chromatography, and size exclusion chromatography. The liquid chromatography was the major shareholder in 2020, owing to factors such as various applications of liquid chromatography to the fields of pharmaceutical chemistry, bioanalysis, antibiotics, metabolomics, proteomics, drug analysis, medical sciences, and plant, agricultural, environmental and food chemistry.
By product, the market is segmented into instruments, consumables, and accessories. In addition, consumable segment classified into columns, syringe filters, vials, tubing, and others include valves, gauges, liners, sealers. Moreover, accessories segment again divided into detectors, autosamplers, pumps and flow meters, fraction collectors, and others includes mixers, regulators, and mobile phase accessories. The consumable segment dominated the global chromatography market in 2020 and is anticipated to continue this trend during the forecast period. This is attributed to, growing adoption of consumables to separate, identify, and analyze various compounds such as vitamins, preservatives, additives, proteins, and amino acids in the pharmaceutical industry.
Based on end user, it is categorized into pharmaceutical & biotechnology company, academic & research institutes, food & beverage company, and others include oil & gas company, and environmental agencies.
The pharmaceutical & biotechnology company acquired the largest share in 2020, and is expected to remain dominant throughout the forecast period. This is attributed to the increase in application of chromatography techniques pharmaceutical & biotechnology company for various purposes such as for identifying and analyzing samples for the presence of chemicals or trace elements, for preparing huge quantities of extremely pure materials, for separating chiral compounds, for detecting the purity of mixture and the unknown compounds present as well as content uniformity, drug development, and validation of drugs.
Key Findings Of The Study
- Based on type, the liquid chromatography held the largest share in the global chromatography market in 2020.
- Based on product, the consumables held the largest chromatography market share in 2020 and is expected to remain dominant throughout the forecast period.
- By end user, the pharmaceutical and biotechnology company dominated the global market in 2020 and is anticipated to continue this trend during the forecast period.
- Based on region, North America is expected to experience growth at the highest rate, registering a CAGR of 4.80% during the forecast period.
North America accounted for the largest share of the global chromatography market in 2020, and is expected to remain dominant throughout the forecast period. This was attributed to the presence of giant biopharmaceutical and pharmaceutical firms in the countries such as the U.S. In addition, increase in adoption of chromatographic techniques for drug discoveries and drug approvals by this biopharmaceutical and pharmaceutical firms further drive the market growth in the region during the forecast period.