Microbiome Sequencing Market Expected to Reach $3,417.09 Million by 2031—Allied Market Research

According to a new report published by Allied Market Research, titled, “Microbiome Sequencing Market," The microbiome sequencing market size was valued for $859.42 million in 2021 and is estimated to reach $3,417.09 million by 2031, exhibiting a CAGR of 14.8% from 2022 to 2031.  

Microbiome sequencing is the method used to determine entire genetic makeup of a specific organism or cell type such as bacteria, virus, fungi, or parasites in the sample. The largest population of microbes in the human body is found in the gut, where it plays a multifaceted role in host biology and dysbiosis. The microbiome sequencing is the analysis of microbial communities found in or on the human body, helping to understand specific diseases such as cancer, cardiovascular disorders, and infectious diseases. In addition, imbalances in microbiome can induce inflammation, release toxic substances, trigger immune system disequilibrium, and cause diseases both in their immediate and distant environment. The goal of microbiome sequencing is to understand the role of microbes in disease and human body, which helps in diagnosing and treating the disease.  

The various objectives of microbiome sequencing are: to take advantage of new, high-throughput sequencing technologies to characterize the human microbiome more fully by studying samples from multiple body sites from each other, to determine whether there are associations between changes in the microbiome and health/disease person by studying several different medical conditions and to provide both standardized data resource and new technological approaches to enable such studies to be undertaken broadly in the scientific community.  

The factors such as rise in R&D activities regarding microbiome and increase in government support & funding for microbiome sequencing research in various regions are anticipated to be microbiome sequencing market trends. Scientists are now developing a far more detailed understanding of the true importance of microbial communities to human health, and significantly, also to diseases that may not originally have been suspected to have a microbiological origin. For instance, according to report of NCIMB 2022, recent research has associated changes in human gut bacteria with conditions including obesity and recurrent infection. In U.S., various research projects related to microbiome sequencing have been funded and supported by government to study the mechanisms and progression of various diseases. For instance, according to report of Microbiome Insights 2022, in U.S., various projects, such as modulating human microbiome function to enhance immune responses against cancer and clinical & applied research strategies for the prevention & control of fungal diseases, are funded by government, which drives the microbiome sequencing market forecast.  

Further, increase in spending for various microbiome R&D activities across the globe is anticipated to contribute to growth of market. For instance, according to report of Biotechnology and Biological Sciences Research Council (BBSRC) 2022, 2 million dollars are expected to be granted for microbiome research activity by UK Research and Innovation Cell to promote research that advances the understanding of the biological function and influence of microbiomes. The microbiome sequencing market analysis is segmented by technique, research, end user and region.

Depending on technique, the market is bifurcated into shotgun sequencing, RNA sequencing, targeted gene sequencing, whole-genome sequencing, and others. The RNA sequencing segment accounted for the largest microbiome sequencing market share owing to the offering of 16S, ITS2 rRNA gene sequencing services by the majority of the players. In addition, the shotgun sequencing segment exhibited the highest growth during the forecast period as it provides whole coverage of microbiome taxonomy including virus which is highly preferred and has short turnaround time  

On the basis of research, the market is classified into outsourced & internal. The outsourcing segment accounted for the largest microbiome sequencing market share in 2021 and is also expected to remain dominant during the forecast period, owing to rise in outsourcing of sequencing to reduce costs and hassles while streamlining the end-to-end process. 

On the basis of end user, the market is categorized into pharmaceutical and biotechnology companies and Academic Institutes and Research centers. The academic institutes and research centers segment occupied highest microbiome sequencing market size in 2021 and is expected to remain dominant during forecast period owing rise in microbiome research activities carried and convenient protocol, shorter operation time, and precision in results.  .  

Region wise, North America had the highest microbiome sequencing market size in 2021, and is expected to maintain its lead during the forecast period, owing to increase in prevalence of infectious and digestive diseases and rise in healthcare infrastructure for research. However, Asia-Pacific is expected to witness highest growth during the forecast period, owing to increase in investments for development of microbiome sequencing techniques and increase in use of microbiomes in genomics and proteomics drives the growth of market during the forecast period. 

Key findings of the study 

• By technique, the RNA sequencing segment was highest contributor to the microbiome sequencing industry in 2021.  
• By research, outsourced segment dominated the market in 2021 with highest CAGR during  
• the forecast period. 
• On the basis of end user, the academic institutes and research centers segment dominated the  microbiome sequencing industry in 2021 with highest CAGR during forecast period.  
• Region wise, North America generated the largest revenue in 2021. However, Asia-Pacific is anticipated to grow at the highest CAGR during the forecast period.