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Recombinant Proteins Market Expected to Reach $5.2 Billion by 2033

 
2022
Recombinant Proteins Market

Report Code : A11233

quote The growth of the recombinant proteins market is driven by advancements in biopharmaceutical research, increasing demand for personalized medicine, rising prevalence of chronic diseases, and expanding applications in drug discovery and development. Additionally, growing investments in biotechnology and the adoption of recombinant proteins in diagnostics and therapeutic areas further fuel market expansion. quote

Roshan Deshmukh - Manager
Life Sciences at Allied Market Research

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According to a new report published by Allied Market Research, titled, “Recombinant Proteins Market," The recombinant proteins market size was valued at $2.5 billion in 2023, and is estimated to reach $5.2 billion by 2033, growing at a CAGR of 7.7% from 2024 to 2033.

Recombinant proteins are proteins produced through recombinant DNA technology, where a gene encoding the desired protein is inserted into a host organism, such as bacteria, yeast, or mammalian cells. This gene is transferred using a vector, like a plasmid, and the host organism's cellular machinery expresses the protein. The protein is then harvested, purified, and utilized in various applications, including drug development, vaccines, and research. Recombinant proteins are crucial in biopharmaceuticals, as they can be engineered for high yield, purity, and specific functionality, enabling advancements in medicine, diagnostics, and biotechnology.

According to recombinant proteins market analysis, increasing prevalence of chronic and infectious diseases is a significant driver of growth in the recombinant protein market. Chronic diseases like cancer, diabetes, and cardiovascular disorders require continuous treatment, thus driving sustained demand for recombinant protein-based therapeutics such as monoclonal antibodies and growth factors. Simultaneously, rise in incidence of infectious diseases, including influenza, hepatitis, and emerging viral outbreaks, has heightened the need for rapid vaccine development and therapeutic proteins.

Recombinant proteins play a pivotal role in creating targeted treatments and vaccines due to their ability to interact precisely with disease-specific pathways. The growing emphasis on personalized medicine further fuels the market’s growth. Personalized medicine tailors treatments as per an individual’s genetic profile, necessitating customized protein-based drugs. Recombinant proteins, such as patient-specific antibodies and growth factors, support precision healthcare by enabling more effective, targeted therapies with fewer side effects. This approach is particularly useful for treating chronic and complex diseases, making it a key driver for recombinant proteins market growth.

According to recombinant proteins market trends analysis initiatives by key industry players are accelerating market expansion. For instance, in May 2024, Wacker Biotech US Inc. announced plans to enhance its production capacities for advanced therapy medicinal products. By expanding its bioprocess development capabilities for pDNA, mRNA, and recombinant proteins, Wacker Biotech aims to support research and pre-clinical development in the U.S. market. Such strategic initiatives not only address growing demand but also improve production efficiency and supply chain resilience. Collectively, the surge in chronic and infectious diseases, growth in demand for personalized medicine, and proactive industry initiatives create a positive growth trajectory for the recombinant proteins market size.

The recombinant proteins industry is segmented into type, application, host cell, end user, and region . On the basis of type, it is segmented into antibodies, hormones, growth factors and cytokines, immune checkpoint proteins, recombinant regulatory protein, virus antigen, and others. The growth factors and cytokines segment dominated the recombinant proteins market share in 2023. This was attributed to due to their widespread use in cell culture, regenerative medicine, and therapeutic development. Their essential role in cell signaling, wound healing, and immune response drives demand, and is supported by increase in research activities and advancements in biopharmaceutical production technologies.

However, the antibodies segment is expected to register the highest CAGR during the forecast period owing to rising demand for monoclonal antibodies in targeted therapies, cancer treatment, and immunological research. Technological advancements in antibody engineering and growth in biopharmaceutical R&D investments further fuel recombinant proteins market growth.

On the basis of application, the market is divided into drug discovery and development, biopharmaceutical production, research, diagnostics, and others. The drug discovery and development segment dominated the recombinant proteins market share in 2023 and is expected to register the highest CAGR during the forecast period. This is attributed to rising demand for targeted therapies and personalized medicine. Advancements in protein engineering, high-throughput screening, and increased biopharmaceutical R&D investments drive the market. Recombinant proteins enable faster drug candidate identification and validation, enhancing development efficiency.

On the basis of host cell, the market is divided into mammalian systems, yeast & fungi, bacterial cells, and others. The mammalian systems segment dominated the market in 2023 and is expected to register the highest CAGR during the forecast period, owing to their ability to produce complex proteins with proper post-translational modifications, such as glycosylation. These systems are essential for manufacturing therapeutic proteins, including monoclonal antibodies, hormones, and enzymes. The growing demand for biologics, coupled with advancements in biomanufacturing technologies, drives the expansion of mammalian systems in recombinant protein production.

On the basis of end user, recombinant proteins industry is classified into pharma & biotechnology companies, academic & research institutes, diagnostic laboratories, and others. The pharmaceutical and biotechnology companies segment dominated the market in 2023 and is expected to register the highest CAGR during the forecast period. This is attributed to high demand for therapeutic proteins, monoclonal antibodies, and vaccines. These companies drive innovation in drug discovery, development, and production, supported by significant R&D investments, advancements in biopharmaceutical technology, and growth in focus on personalized medicine and targeted therapies.

Region wise, North America was the largest shareholder in the recombinant protein market in 2023, owing to its strong pharmaceutical and biotechnology sectors, advanced research facilities, and high healthcare investments. The presence of major biopharmaceutical companies, coupled with government funding for research and development, further fuel market growth in the region. However, according to recombinant proteins market forecast analysis Asia-Pacific is anticipated to register the highest CAGR during the forecast period owing to increasing investments in biotechnology, expanding healthcare infrastructure, and rising demand for recombinant proteins in drug development and therapeutics. The region's growing pharmaceutical industry, coupled with favorable government policies and research initiatives, further drives market growth.

Segment Highlights

  • On the basis of type, the Growth Factors and Cytokines segment dominated the market share in 2023. However, the Antibodies segment is anticipated to grow at the highest CAGR during the forecast period.
  • On the basis of application, the Drug Discovery and development segment dominated the market share in 2023 and is anticipated to grow at the highest CAGR during the forecast period.
  • On the basis of host cells, the Mammalian systems segment dominated the market share in 2023 and is anticipated to grow at the highest CAGR during the forecast period.
  • On the basis of end user, the pharmaceutical and biotechnology companies segment dominated the market share in 2023 and is anticipated to grow at the highest CAGR during the forecast period. 
  • Region wise, North America generated the largest revenue in 2023. However, Asia-Pacific is anticipated to grow at the highest CAGR during the forecast period.

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quote Recombinant Proteins Market By Type (Antibodies, Hormones, Growth Factors and Cytokines, Immune checkpoint proteins, Recombinant Regulatory Protein, Virus antigen, Others), By Application (Drug Discovery and development, Biopharmaceutical production, Research, Diagnostics, Other), By Host Cell (Mammalian systems, Yeast and Fungi, Bacterial Cells, Others), By End User (Pharma and Biotechnology Companies, Academic and Research Institutes, Diagnostic Laboratories, Others): Global Opportunity Analysis and Industry Forecast, 2024-2033 quote

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