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Vietnam Plasma Fractionation Market Expected to Reach $79.03 Million by 2027

 
 

quote The plasma fractionation market in Vietnam is majorly driven by prevailing disease conditions in the population, coupled with growth in geriatric individuals vulnerable to many diseases, thereby, leading to rise in demand for plasma derived approaches to treat diseases, specifically immune and neurological disorders. Moreover, plasma derived treatments are precise and proteins used in the procedures possess properties that are unique to them. As a result, there are fewer substitutes available in the market. However, considerable regulatory burden on manufacturing and logistics of plasma fractionation is expected to impede the market growth in Vietnam. quote

Onkar Sumant
Manager, Healthcare at Allied Market Research

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According to a new report published by Allied Market Research, titled, “Vietnam Plasma Fractionation Market by Product, Application, and End User: Opportunity Analysis and Industry Forecast, 2020–2027," The Vietnam plasma fractionation market size was valued at $56.62 million in 2019, and is expected to reach $79.03 million by 2027, registering a CAGR of 5.3% from 2020 to 2027. Blood is made up of solid components such as platelets, red blood cells, white blood cells, and a liquid component called plasma. Plasma is a straw-colored fluid, comprising 90% water and 10% dissolved gases, proteins, nutrients, ions, and waste materials. It contains a wide variety of proteins that can be isolated on the basis of their solubility characteristics particular to each protein at specific conditions of ethanol concentration, pH, temperature, ionic strength, and protein concentration. This enables extraction of these proteins through sequential precipitation allowing the isolation of certain proteins by centrifugation, filtration, and chromatography. Plasma fractionation is extensively used for manufacturing immunoglobulins and albumin along with several protein derivatives such as thrombin, protein C, factor IX, and factor VIII as key intermediates. These plasma derivatives have numerous applications in the fields of hematology, immune disorders, infectious diseases, shock, burns, restoring blood volume in trauma as well as rare chronic conditions. For instance, clotting factors in blood plasma are used for treating coagulation disorders such as disseminated intravascular coagulation or hemophilia. In critical care conditions, plasma is often prescribed to prevent and stop bleeding. Moreover, some of these derivatives are declared as essential medicines by WHO as there are no substitutes available in the market, thus creating various opportunities for the manufacturers.

Vietnam, on the other hand, is a potentially large healthcare market wherein the presence of public sector is overpowering the private sector, comprising of more than 85% of the hospitals and commune health stations across the country. As per World Bank Group, Vietnam is considered as a middle-income country with a healthcare expenditure of 5.53% of its GDP. To succeed as a middle-income country, the Vietnamese government is currently focusing on building core public health capacities in workforce development, diseases surveillance, emergency management, laboratory systems, and others for prevention and control of diseases. In addition, based on the current demographic trends in Vietnam, it is projected to become an aged society by 2035. Thus, this estimated change in demographics is anticipated to increase the onset of different diseases among the Vietnamese population in the coming future thereby resulting in surged demand for novel and innovative disease management approaches. Moreover, owing to the long-lasting effect of the herbicides used in Second Indochina War (Vietnam War), the population is already bearing some major illnesses, correspondingly having a similar impact on the future generations in the country.

According to the data published by U.S. Department of Veterans Affairs in 2020, some of these illnesses include chronic B-cell leukemia, Hodgkin’s disease, multiple myeloma, Non-Hodgkin’s lymphoma, respiratory cancers, Chloracne, and diabetes mellitus type 2. Considering the current unmet medical needs within the country, the demand for the plasma products is expected to increase, justifying the ever-increasing incidences of immunological disorders, hemophilia, metabolic, and neurological disorders. Therefore, the country provides lucrative opportunities to the domestic pharmaceutical companies for setting up their plasma fractionation plants to meet the population demand. Considering the country’s need to work towards self-sufficiency in plasma fractionated products, in 2015, a local firm “An Phat Pharmaceutical and Medical Equipment JSC” proposed and received a license to develop Vietnam’s 1st plasma fractionation factory. The plant was scheduled to start the production of albumin, FVIII, prothrombin, IVIG, and other plasma derivatives from 2018. However, considering the unmet Good Manufacturing Practice (GMP) standards, the production discontinued. Later, in 2019, the blood bank in “Ho Chi Minh City Blood Transfusion Hospital” was declared to meet the GMP requirements as per European standards for treatment process of plasma. Currently, Vietnam does not have their own plasma manufacturing plant, it imports the plasma fractionated products namely the coagulation factors VIII, factor IX, and albumin, and gamma globulin products from developed countries. Thus, the blood bank provides an opportunity for Vietnam to manufacture their own plasma products and exchange it overseas. 

The pre-existing medical conditions in the Vietnamese population, owing to the side effects of the Second Indochina War coupled with aging population is anticipated to drive the growth of the Vietnam plasma fractionation market. In addition, unavailability of the substitutes for plasma fractionated products is expected to drive the market growth in Vietnam, since these products cannot be replaced owing to their histocompatibility, post-translational modifications, and absence of recombinant approaches for replication of these proteins. On the contrary, stringent regulations, both in terms of higher quality standards of the products and integrated logistics to source and collect the blood plasma and timely delivery to clinics, hospitals, and pharmacies are the anticipated factors to hinder the market growth. However, the unmet medical needs of the Vietnamese population are possibly expected to provide profitable opportunities for the plasma fractionation manufacturers to expand their geographical reach. Furthermore, owing to COVID-19 outbreak, trade and transport restrictions, quarantine measures, cross-border movement controls and disruptions in production have reduced the supply of blood and blood components across the Vietnam, thereby adversely affecting blood supply chain activities. Due to the pandemic, there is decrease in the supply of critical products and equipment used in plasma & plasma component collection, which might further disrupt the manufacturing of plasma derivatives in the country. The suspension of several blood donation programs and campaigns amid nationwide lockdown is expected to possibly drag the market growth. Nonetheless, the pharmaceutical companies operating in the Vietnam plasma fractionation market are likely to benefit from the newly launched plasma therapies and products for treating COVID-19 patients, on an account of the increasing number of COVID-19 patients across the country.

The Vietnam plasma fractionation market is segmented on the basis of product, application, and end user. By product, the market is classified into albumin, immunoglobulins, coagulation factor VIII, and Coagulation factor IX. Under immunoglobulin segment, the Vietnam plasma fractionation market is further bifurcated in to intravenous immunoglobulin (IVIG) and subcutaneous immunoglobulin (SCIG). By application, the market is categorized into neurology, hematology, immunology, critical care, and others. By end user, the Vietnam plasma fractionation market is bifurcated into hospitals and clinical research laboratories.

Key Findings Of The Study 

  • Based on product, the immunoglobulin segment was the highest contributor in 2019, growing at a CAGR of 5.6% during the forecast period.

  • Based on application, the neurology segment was the largest contributor in 2019, and is expected to grow at a CAGR of 5.9%.

  • On the basis of end user, the hospitals segment is likely to dominate the Vietnam plasma fractionation market in the forecast year.

The key players operating in the Vietnam plasma fractionation market are Baxter International Inc., Biotest AG, Bio Products Laboratory Ltd., Getz Healthcare, Grifols SA, Kedrion Biopharma, Octapharma, Novo Nordisk, Sanova Healthcare, Sanquin blood supply foundation, and Takeda pharmaceutical company limited. 

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quote Vietnam Plasma Fractionation Market by Product (Albumin, Immunoglobulins, Coagulation Factor VIII, and Coagulation Factor IX), Application (Neurology, Hematology, Immunology, Critical Care, and Others), and End User (Hospitals and Research Laboratories): Opportunity Analysis and Industry Forecast, 2020–2027 quote

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