Report Code: A05144 | Nov 2023 | Pages: NA | ||
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Pandemic disrupted the entire world and affected many industries.
Get detailed COVID-19 impact analysis on the Cholesterol-lowering Drug Market
Request Now !Cholesterol is an organic molecule that belongs to the group of steroids and is a type of lipid. It is biosynthesized by all animal cells, and is an essential structural component of animal cell membranes. The significance of cholesterol is the biosynthesis of steroid hormones such as estrogen and testosterone, as well as bile acid and vitamin D. About 80% of cholesterol production occurs in liver and intestines, and the rest comes from dietary sources such as meat, poultry, eggs, fish, and dairy products. Although cholesterol is fundamentally required by the body, more than 240 mg/dl is considered as high cholesterol. A total cholesterol of 200 mg/dl or lower is acceptable, and 200–240 mg/dl is considered borderline high. This elevated level of cholesterol in the blood is termed as hypercholesterolemia. High cholesterol may be a consequence of unhealthy diet, obesity, genetic diseases, or other diseases such as type 2 diabetes and an underactive thyroid.Â
The global cholesterol lowering drug market is anticipated to grow modestly during the forecast period. Some of the factors anticipated to boost the cholesterol lowering drug market growth are emergence of new drug classes, changes in lifestyles, lack of exercise, and increase in intake of saturated & trans-fat. In addition, increase in smoking and alcohol consumption escalate the risk of high cholesterol, thus driving the market growth. However, severe side effects of statins causing rhabdomyolysis and availability of generic drugs of leading brands are projected to restrain the market growth during the forecast period. On the contrary, lucrative opportunities in emerging economies are expected to provide significant prospects for the manufacturers in industry.
Emergence of more effective therapies such as PCSK9 inhibitors, bempedoic acid, and the upcoming drug by The Medicines Company, inclisiran is anticipated to expand the range of clinical indications. Inclisiran is an upcoming drug, which may enter the market by 2020, and is expected to become the third potent drug after the two PCSK9 inhibitors, Repatha (Amgen) and Praluent (Sanofi/Regeneron). Former CEO of the Medicines Company, Dr. Clive Meanwell indicated that the company is likely to keep cost lower than that of PCSK9 inhibitors to bring the medicine to the masses. Furthermore, inclisiran has significant advantage over the two, for its requirement of only 2 dose per year. For comparison, PCSK9 needs to be dosed every two weeks.
This report segments the cholesterol-lowering drug market based on drug class, disease type, and region. Depending on drug class, the market can be classified as statins, bile acid sequestrants, cholesterol absorption inhibitors, fibric acid derivatives, PCSK9 inhibitors, combination, and others. By disease type, it categorized into hypercholesterolemia, cardiovascular diseases, and hyperlipidemia. Region wise, it is analyzed across North America, Europe, Asia-Pacific, and LAMEA.Â
The report provides a comprehensive analysis of the key players operating in the global cholesterol lowering drug market players such as AstraZeneca, Merck & Co., Pfizer Inc., Kowa Company, Daiichi Sankyo Company, Limited, AbbVie Inc., Novartis AG, Sanofi S.A., Amgen Inc., and Bristol-Myers Squibb (BMS). The other players in the value chain includes Covis Pharmaceuticals, Inc., Lupin Pharmaceuticals, Inc., Bausch Health Companies Inc., Aegerion Pharmaceuticals, Aralez Pharmaceuticals, and others.
Cholesterol-lowering Drug Market Report Highlights
Aspects | Details |
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By Drug Class |
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By Disease type |
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By Region |
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Key Market Players | Kowa Company, Novartis AG, AbbVie Inc., Daiichi Sankyo Company Limited, Merck & Co., Bristol-Myers Squibb (BMS), Amgen Inc., Sanofi S.A., AstraZeneca, Pfizer Inc. |
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