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2019
Early Toxicity Testing Market

Early Toxicity Testing Market by Technique (In Vivo, In Vitro, and In Silico), and End User (Pharmaceuticals Industry, Food Industry, Chemicals Industry, Cosmetics Industry, and Others): Global Opportunity Analysis and Industry Forecast, 2018–2025
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A00500
Pages: 210
May 2019 | 13361 Views
Author(s) : Sayali Shinde , Sanjivan Gill , Onkar Sumant
Tables: 84
Charts: 60
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Early Toxicity Testing Market Outlook - 2025

The early toxicity testing market accounted for $739 million in 2017, and is expected to reach $1,301 million by 2025, registering a CAGR of 7.3% from 2018 to 2025.Toxicity is the degree of threat posed by a substance to the living organism. The effects of chemical substance on the body are studied to choose a potential drug candidate during the development of newer molecules. Early toxicity testing is carried out at pre-clinical stages of a drug development process and is essential as toxicity serves as the major reason for the failure of potential drug candidates in the later stages of drug development leading to huge financial loss to companies. Well designed and executed preclinical studies are critical to the success of any drug development program. Therefore, they must reliably assess the safety of a new drug entity, laying the groundwork for clinical trials and ultimately, regulatory approval. Moreover, these tests are necessary as they can prevent financial losses that occur during the failure of drugs in further late stages of drug development.

The global early toxicity testing market is expected to witness significant growth during the forecast period, owing to increase in the R&D activities and rise in stringent regulatory authorities concerning public healthcare welfare. In addition, technological advancements in in vitro technique, rise in adoption of in vitro models in the global early toxicity testing industry worldwide, and surge in adoption of early toxicity testing in the various industries further fuel the market growth. However, limitations associated with preclinical testing hamper the market growth. Furthermore, the technological advancements related to early toxicity testing provide opportunities for the growth of the early toxicity testing market during the forecast period.

Early Toxicity Testing Market Segmentation

The early toxicity testing market is segmented based on technique, end user, and region to provide a detailed assessment of the market. Based on technique, the market is divided into in vivo, in vitro, and in silico. Based on in vitro, it is further divided into in vitro toxicity testing market by assays and in vitro toxicity testing market by toxicity endpoints. The in vitro toxicity testing market by assays is further segmented into enzyme toxicity assays, bacterial toxicity assays, cell-based ELISA & western blots, receptor binding assays, and other assays. The in vitro toxicity testing market by toxicity endpoints is further divided into dermal toxicity, systemic toxicity, carcinogenicity, ocular toxicity, skin sensitization and irritation, neurotoxicity, organ toxicity, and other toxicity endpoints. By end user, it is categorized into pharmaceutical industry, food industry, chemicals industry, cosmetics industry, and other industry. Based on region, the early toxicity testing market size is analyzed across North America (U.S., Canada and Mexico), Europe (Germany, France, the UK, and rest of Europe), Asia-Pacific (China, Japan, India, Australia, and rest of Asia-Pacific), and LAMEA (Brazil, South Africa and rest of LAMEA).

Early Toxicity Testing Market

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Segment review

Based on technique, the market is divided into in vivo, in vitro, and in silico. The in vitro segment was the largest contributor to the early toxicity testing market in 2017 and is expected to maintain its dominant position throughout the analysis period. In vitro toxicity methods use different laboratory techniques and cell lines to assess the possible adverse effects of different drugs and chemicals on the human health. Cost-effective nature of this technique, technological advancement, and stringent regulation for animal usage during diagnostic procedures majorly drive the growth of the early toxicity testing market growth. On the other side, the in silico segment is the fastest growing segment during the forecast period, owing to the rise in its adoption due to advantages offered by the technique. In silico techniques have revolutionized the drug discovery process as these techniques are not only applied to find the new targets and new molecule with high affinity to those targets but also used to determine the metabolic pathways of those active molecules. In addition, these techniques are computer-based that eliminate animal sacrifice, which is another factor that contributes toward the early toxicity testing market growth.

Early Toxicity Testing Market by Technique

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According to the early toxicity testing market analysis, the end users segment is classified into pharmaceutical industry, food industry, chemicals industry, cosmetics industry, and other industries. The pharmaceutical segment occupied the highest share of early toxicity testing market size in the year 2017. Cosmetic industry segment registered fastest growth rate during forecast period, owing to rise in aesthetic consciousness, surge in disposable income of general public across the globe, increase in new product launches in the field of cosmetics and stringent government guidelines monitoring the nature of chemicals used in cosmetic products.

Early Toxicity Testing Market by End User

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Region wise, Europe accounted for the largest early toxicity testing market share in 2017 owing to surge in R&D related to drug discovery and stringent guidelines regulating the safety of chemicals used in different products used by public. Other factors that fuel the growth of the market in this region include the wide and easy availability of toxicity testing devices and products and presence of highly trained technical professionals. Asia-Pacific is expected to register the fastest growth during the forecast period due to rise in awareness related to toxicity of compounds and rise in R&D investments related to healthcare.

Early Toxicity Testing Market by Region

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Key Benefits for Early Toxicity Testing Market:

  • This report entails a detailed quantitative analysis along with the current early toxicity testing market trends of the market from 2017 to 2025 to identify the prevailing opportunities along with the strategic assessment of the global market.
  • The early toxicity testing market forecast is studied from 2018 to 2025.
  • The market size and estimations are based on a comprehensive analysis of key developments in the early toxicity testing industry.
  • A qualitative analysis based on innovative products facilitates strategic business planning.
  • The development strategies adopted by the key market players are enlisted to understand the competitive scenario of the market.

Key Market Segments

  • BY TECHNIQUE
    • In Vivo
    • In Vitro
      • Enzyme toxicity assays
      • Bacterial toxicity assays
      • Cell-based ELISA and western blots
      • Tissue culture assays
      • Receptor binding assays
      • Others
    • In vitro early toxicity testing market, by toxicity end-point
      • Systemic toxicity
      • Carcinogenicity
      • Ocular toxicity
      • Skin sensitization and irritation
      • Genotoxicity
      • Neurotoxicity
      • Organ toxicity
      • Others
    • In silico
  • BY END USER
    • Pharmaceuticals Industry
    • Food Industry
    • Chemicals Industry
    • Cosmetics Industry
    • Other Industries
  • BY REGION
    • North America
      • U.S.
      • Canada
      • Mexico
    • Europe
      • Germany
      • France
      • UK
      • Rest of Europe
    • Asia-Pacific
      • India
      • China
      • Japan
      • Australia
      • Rest of Asia-Pacific
    • LAMEA
      • Brazil
      • South Africa
      • Rest of LAMEA


Key Market Players

  • AGILENT TECHNOLOGIES, INC.
  • BIOANALYTICAL SYSTEMS, INC.
  • BRUKER CORPORATION
  • DANAHER CORPORATION (BECKMAN COULTER, INC.)
  • EVOTEC AG (CYPROTEX)
  • ENZO BIOCHEM, INC. (ENZO CLINICAL LABS, INC.)
  • GENERAL ELECTRIC COMPANY (GE HEALTHCARE
  • MYRIAD GENETICS, INC. (MYRIAD RBM.)
  • PERKINELMER INC.
  • THERMO FISHER SCIENTIFIC, INC.
 

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Early toxicity testing is the analysis of chemical entities in the pre-clinical phases to check their compatibility for the clinical trial to be performed in humans. In accordance to several interviews conducted, the adoption of early toxicity testing across the globe is expected to witness significant growth with rise in research conducted toward the development of new drugs. In addition, the early toxicity testing gains traction due to high number of drug failures in the later stages of drug testing. These stages are very expensive to perform and later the failure causes even more financial loss of the company. Moreover, there have been remarkable technological advancements to improve the process of drug development. The increase in stringent regulations concerning public welfare and replacement of in vivo models by in vitro models are some the factors that boost the growth of the early toxicity testing market.

In addition, surge in healthcare investments worldwide is another major factor that drives the market growth. However, limitations of preclinical testing are expected to restrain the market growth. A rapid advancement in in silico platforms serves as an opportunity to early toxicity testing market. Europe garnered the largest share of this market due to rise in research activities related to drug development, and stringent regulations governing the safety associated with products, while Asia-Pacific is expected to grow at the fastest pace, owing to surge in healthcare investments in the country.

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