Report Code: A31722 | Pages: 250 | ||
Tables: 77 | Charts: 56 |
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The global fatty bases for suppositories market size was valued at $197.9 million in 2021, and is projected to reach $339.5 million by 2031, growing at a CAGR of 5.6% from 2022 to 2031. Suppositories are solid or semi-solid dosages in a variety of shapes and weights that are designed to be inserted into a person's vaginal, rectal, or urethral orifice. At body temperature, the suppositories melt or dissolve. This suppository has protective or therapeutic properties that deliver systemic action.
The COVID-19 outbreak caused severe supply chain disruption across the globe, thus, hampering the manufacturing of therapeutic suppositories. The stringent lockdowns forced many manufacturing plants to shut down due to labor shortages. This, in turn, ultimately lowered the demand for fatty bases for suppositories.
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Suppositories are classified as rectal, vaginal, and urethral suppositories depending on where they are inserted. Suppositories may not be the most comfortable product you've ever used. They can, make it easier to take medication that you can't swallow or that your stomach or intestines won't absorb properly. The ideal suppository base such as fatty bases should be non-irritating, non-toxic, inert, easily formed by molding or compression, and compatible with medicaments. It should also disintegrate or dissolve in the existence of mucous secretions or else melt at body temperatures to allow for the discharge of the medication. The fatty bases for suppositories play a crucial role in both the extent and rate of the release of medications as with the ointment bases. Fatty bases consist of synthetic triglyceride mixtures of Cocoa butter or obroma oil as a suppository base. This mixture is used majorly due to its ideal qualities. At a room temperature of 15° to 25°C, it is a rigid amorphous solid, but at 30° to 35°C, i.e., it melts to a blend at body temperature. While preparing suppositories with a base of cocoa butter, the base must not be heated above 35°C as it is a polymorphic compound. If this compound is inflamed will transform into a metastable structure which melts in the 25° to 30°C range. Hence, the finished suppository would not be used as it melts at room temperature.Â
The global fatty bases industry for suppositories is growing significantly due to the advantageous properties of fat-based suppositories, such as retention of large volumes, rapid absorption of many low molecular weight medicines, and the potential for lymphatic system absorption. A further factor driving demand for fat-based suppositories and the expansion of the market is their importance in the drug delivery of elderly and pediatric patients. Furthermore, the use of fatty excipients in the management of viral infections is likely to open up lucrative prospects for market expansion. Although fatty bases for suppositories have a long history of use in rectal and vaginal drug delivery, the current global market for these products is constrained primarily by a lack of consumer acceptance and willingness to use rectal products. Additionally, it is thought that the difficulties in producing oil-based suppositories will somewhat restrain the market expansion.
The modern healthcare industries are looking for improved medications and better alternatives that could help patients recover from infectious diseases such as allergies, anxiety, constipation, fever and many more. There is a good chance of developing an antiretroviral suppository drug delivery system, according to ongoing research conducted globally by numerous institutions, biotech companies, and pharmaceutical companies. Topical vaginal and rectal microbicides have demonstrated efficacy in the management of viral infections and disease and are essential in the delivery of antiretroviral therapy. These delivery systems, which are currently undergoing significant development, give high-risk patients accessible and efficient options. Numerous methods are currently being developed and researched for topical antiviral drug delivery systems via the vaginal and rectal routes. These factors will significantly increase the fatty bases for suppositories market opportunity worldwide.The global fatty bases for suppositories market is segmented on the basis of base type and region. By base type, the market is segmented into hard fat,  water miscible base, and emulsifying bases. By region, the market is analyzed across North America, Europe, Asia-Pacific, and LAMEA.
The fatty bases for suppositories market is segmented into base type and Region.
By base type, the emulsifying bases sub-segment is projected to hold the major Fatty Bases for Suppositories Market Share in forecasted years. Emulsions are combinations of two or more types of liquids, one of which is spread throughout the other as tiny or even ultra-small droplets. These are typically created from the components of liquids, either naturally or more frequently via the use of mechanisms such as agitation, as long as the fluids being combined are not mutually soluble. Emulsions are believed to be stabilized by substances that create films on the droplet's surface or by those that give them a certain degree of mechanical stability. These are predicted to be the major factors affecting the fatty bases for suppositories market size during the forecast period too.
By region, Europe is predicted to have a dominant market share in the forecasted years. This is mainly due to the rising patients of gynecological diseases and urology disorders in the region. For example, as per a recently published report, in the Europe, Bacterial Vaginosis (BV) is one of the most common bacterial infections and approximately 30% of women of reproductive age suffer from such diseases. These factors may lead to foster the fatty bases for suppositories market growth of the Europe market, in the forecast period.
The key players profiled in this report include Unither, Bliss GVS Pharma Ltd., Delpharm, ATRAL, Aenova Holding GmBH, FAMAR, LGV (Laboratories Mayoly Spindler), and Priyans Drugs.
Impact of COVID-19 on the Global Fatty Bases for Suppositories Industry
Fatty Bases for Suppositories Market Report Highlights
Aspects | Details |
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Market Size By 2031 | USD 339.5 million |
Growth Rate | CAGR of 5.6% |
Forecast period | 2021 - 2031 |
Report Pages | 250 |
By Base Type |
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By Region |
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Key Market Players | STEARINERIE DUBOIS, CD Formulation, Croda International Plc, IOI Oleo GmbH, SpecializedRx Products, LLC, Dow, Tianshui Huayuan Pharmaceutical Equipment technology Co.,ltd, Gattefossé |
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Over the anticipated period, the market growth is anticipated to be aided by the rising demand for fat-based suppositories due to their benefits, including the quick absorption of several low molecular weight drugs and the potential for lymphatic system absorption. In addition, the growth of the fatty bases for suppositories market is driven by increase in the geriatric population. In pediatrics populations, the rectal route is a great alternative for drug delivery. The demand for suppositories is likely to propel the market growth in the coming years. However, lack of flexibility in commercially supplied suppositories' dosage leads to underuse and scarcity. Moreover, it is thought that the difficulties in producing oil-based suppositories may somewhat restrain the market expansion. On the other hand, increase in geriatric population worldwide is contributing to the growth of the market. According to The World Health Organization, between 2015 and 2050, the proportion of the world's population over 60 years will nearly double from 12% to 22% and by 2030, one in six people in the world will be aged 60 years or over. At this time the share of the population aged 60 years and over will increase from 1 billion in 2020 to 1.4 billion by 2030.
Among the analyzed regions, Europe is expected to account for the highest revenue in the market by the end of 2031, followed by Asia-Pacific, North America, and LAMEA. This is mainly due to the rising patients of viral infection diseases and urology disorders in the region.
A. Rising demand for fat-based suppositories due to their benefits, including the quick absorption of several low molecular weight drugs and the potential for lymphatic system absorption. In addition, the growth of the pharmaceutical suppositories market is driven by increase in the geriatric population and is estimated to generate excellent opportunities in the fatty bases for suppositories market.
A. Unither, Bliss GVS Pharma Ltd., Delpharm, ATRAL, Aenova Holding GmBH, FAMAR, LGV (Laboratories Mayoly Spindler), and Priyans Drugs are the top companies in the fatty bases for suppositories market.
A. The emulsifying bases sub-segment acquired the maximum share of the global fatty bases for suppositories market in 2021.
A. Europe region will provide more business opportunities for the global fatty bases for suppositories market in future.
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