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Gene Editing Market: Global Opportunity Analysis and Industry Forecast, 2020-2027

A10973
Pages: NA
Jun 2021 | 66 Views
 
Author(s) : Onkar Sumant
Tables: NA
Charts: NA
 

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Genome editing (also called gene editing) is a group of technologies that give scientists the ability to change an organism's DNA. These technologies allow genetic material to be added, removed, or altered at particular locations in the genome. Several approaches to genome editing have been developed. Genome editing is of great interest in the prevention and treatment of human diseases. Currently, most research on genome editing is done to understand diseases using cells and animal models. Scientists are still working to determine whether this approach is safe and effective for use in people. It is being explored in research on a wide variety of diseases, including single-gene disorders such as cystic fibrosis, hemophilia, and sickle cell disease. It also holds promise for the treatment and prevention of more complex diseases, such as cancer, heart disease, mental illness, and human immunodeficiency virus (HIV) infection.

Market scope and structural analysis:

Report Metric

Details

  Market size available for years

  2019–2027

  Base year considered

  2019

  Forecast period

  2020–2027

  Forecast units

  Value (USD)

  Segments covered

  Type, Application, End-users, Region

  Regions covered

•North America (U.S., Canada, Mexico)

•Europe (France, Germany, UK, Italy, Spain, Rest of Europe)

•Asia-Pacific (Japan, China, India, Australia, South Korea, Rest of Asia-Pacific)

•LAMEA (Brazil, South Arabia, South Africa, Rest of LAMEA)

  Companies covered

Addgene, Allele Biotech, Bio-Rad, Takara Bio, CRISPR Therapeutics, DNA, Integrated DNA Technologies, OriGene Technologies, Precision Biosciences, GE Healthcare Dharmacon Inc., GeneCopoeia, Inc., GenScript Corporation, Horizon Discovery Group plc, Merck Millipore Limited, Sangamo Biosciences, Inc., Agilent Technologies, Inc., Thermo Fisher Scientific, Caribou Biosciences, Inc.

 

Covid-19 Scenario analysis:

Covid-19 has changed life as we know it. It has also accelerated already rapid trends in innovation and collaboration across the scientific community. As the pandemic spreads across the globe, researchers are racing to develop diagnostics, vaccines and treatments. In the pursuit of new solutions to tackle SARS-CoV-2, the novel coronavirus that causes Covid-19, researchers have been turning to machine learning, AI and high-throughput experimental automation that aid in development. Another powerful tool they are using to accelerate the process is CRISPR. This gene-targeting and gene-editing technology, based on the mechanism that bacteria naturally use to fight viruses, is already proving useful in our joint fight against this new virus. The SARS-CoV-2 is essential to isolating infected patients and managing appropriate healthcare responses. Recently, researchers at MIT published a rapid CRISPR-Cas13-based COVID-19 detection assay protocol. Since CRISPR can be modified to target nearly any genetic sequence, it can be used to detect SARS-CoV-2 RNA in a patient sample. Hence, the gene editing market is on an upward market growth as the technology will be a requirement during testing as well finding a vaccine.

Top impacting factors: Market Scenario Analysis, Trends, Drivers and Impact analysis:

Drivers:

Technological advancements:

A recent genome editing technology is known as CRISPR-Cas9, which is short for clustered regularly interspaced short palindromic repeats and CRISPR-associated protein 9. The CRISPR-Cas9 system has generated a lot of excitement in the scientific community because it is faster, cheaper, more accurate, and more efficient than other existing genome editing methods. CRISPR-Cas9 was adapted from a naturally occurring genome editing system in bacteria. The bacteria capture snippets of DNA from invading viruses and use them to create DNA segments known as CRISPR arrays. The CRISPR arrays allow the bacteria to "remember" the viruses (or closely related ones). If the viruses attack again, the bacteria produce RNA segments from the CRISPR arrays to target the viruses' DNA. The CRISPR-Cas9 system works similarly in the lab. Researchers create a small piece of RNA with a short "guide" sequence that attaches (binds) to a specific target sequence of DNA in a genome. This technology has boosted the market growth because it is very cost efficient and quick.

New diseases and increased fatalities:

Infectious diseases are constantly on the rise. For instance, according to the World Health Organization (WHO) report in 2018, infectious diseases kill more than 17 million people per year. In addition to that, according to the AP-NORC (a research initiative by the Associated Press and the University of Chicago) survey in 2018, out of 1,067 adults in the US surveyed, 71% are in favor of gene editing for the treatment of incurable, hereditary diseases such as Huntington's disease and 67% of Americans support the use of gene editing to prevent diseases such as cancer. The increase in infectious diseases acts as a major driver for the gene editing market. Gene editing techniques are used for detection of infectious diseases such as HIV. Infectious diseases are caused by microorganisms like bacteria, viruses, fungi, and parasites. Gene therapy treats the infectious diseases by blocking the replication of the infectious agent that causes the disease at the extracellular level. Gene editing introduces new genetic material into the cells of living organisms with the intention of treating the diseases.

Restrains:

Ethical concerns arise when genome editing, using technologies such as CRISPR-Cas9, is used to alter human genomes. Most of the changes introduced with genome editing are limited to somatic cells, which are cells other than egg and sperm cells. These changes affect only certain tissues and are not passed from one generation to the next. However, changes made to genes in egg or sperm cells (germline cells) or in the genes of an embryo could be passed to future generations. Germline cell and embryo genome editing bring up a number of ethical challenges, including whether it would be permissible to use this technology to enhance normal human traits (such as height or intelligence). Based on concerns about ethics and safety, germline cell and embryo genome editing are currently illegal in many countries, thereby restraining market growth.

Key segments covered:

Segments

Sub-segments

  Type

  • Restriction Enzymes: the Original Genome Editor
  • Zinc Finger Nucleases (ZFNs): Increased Recognition Potential
  • TALENs Gene Editing: Single Nucleotide Resolution
  • CRISPR-Cas9 Gene Editing: Genome Editing Revolutionized
  • Others

  Application

  • Cell Line Engineering
  • Vaccine development
  • Diagnosis
  • Animal Genetic Engineering
  • Plant Genetic Engineering
  • Other Applications

  End Users

  • Biotechnology & Pharmaceutical Companies
  • Diagnostic Centres
  • Academic & Government Research Institutes
  • Contract Research Organizations

  Region

  • North America
  • Europe
  • Asia-Pacific
  • LAMEA

 

Key benefits of the report:

  • This study presents the analytical depiction of the global Gene editing industry along with the current trends and future estimations to determine the imminent investment pockets.
  • The report presents information related to key drivers, restraints, and opportunities along with detailed analysis of the global Gene editing market share.
  • The current market is quantitatively analyzed from 2020 to 2027 to highlight the global Gene editing market growth scenario.
  • Porter’s five forces analysis illustrates the potency of buyers & suppliers in the market.
  • The report provides a detailed global Gene editing market analysis based on competitive intensity and how the competition will take shape in coming years.

Questions answered in the Gene editing Market research report:

  • What are the leading market players active in the Gene editing market?
  • What the current trends will influence the market in the next few years?
  • What are the driving factors, restraints, and opportunities in the market?
  • What are the projections for the future that would help in taking further strategic steps?
 
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