Livers are essential organs in the human body that carry out various principal duties that incorporate protein production, bile production for digestion, synthesis of blood clotting factors, detoxification, and glucose storage in the form of glycogen. Liver cells also have an exceptional capability which helps in the regeneration of the liver from any damage. This function helps in understanding the cellular and molecular connectivity of the liver tissues.
Liver models are developed so that they can layout a virtual ecosystem that impersonates the functions of the liver and also helps in acknowledging the molecular actions. Advanced liver models can reproduce human liver anatomy, physiology, and also the functions of the human liver. These models are called organoids. These models have replaced the liver animal models. Human liver models have many advantages when compared to animal models. Human liver models are utilized during the screening process of new drugs for liver toxicity research.
The human liver model is made from a single fetal liver progenitor cell which ultimately modifies into a specialized liver cell. This immature progenitor cell is self-assembled in a disc. The human liver model can generate hepatocytes and can carry out the functions of the liver. These models can produce bioengineered liver tissues which are fully functional for the transplantation.
COVID-19 scenario analysis:
Pharmaceutical and biotech companies together with governments around the globe are working to address the COVID-19 outbreak, from supporting the development of vaccines to planning for medicines supply chain challenges. Currently, around 115 vaccine candidates and 155 molecules are in the R&D pipeline. Moreover, commonly used drugs such as Hydroxychloroquine have witnessed a dramatic surge in demand for the management of COVID-19. Such high demand for these drugs has presented huge opportunities for manufacturers of COVID-19 management drugs, as many developed countries are short of these drugs. Owing to the demand for vaccine and treatment drugs for COVID-19, the pharmaceutical and biotechnology industry is expected to witness a significant growth in the future.
Owing to such factors, COVID 19 is expected to have a significant impact on the Human Liver Models market.
Top impacting factors: Market Scenario Analysis, Trends, Drivers and Impact Analysis:
Focus has been increasing on developing options for animal testing models is creating new opportunities for human liver models, there has also been a rise observed in the research investments and venture capital funding for the research on the liver models, actions taken by the key players and the government to spread awareness about liver models, research programs are also been favored which is leading to the growth of the human liver models market.
There has also been a significant rise in the frequency of non-alcoholic fatty liver disorder and the requirement for drug toxicity detection at an earlier stage which helps in minimizing the financial losses in the later stages.
Additionally, the initiatives for creating awareness for the liver models are creating new opportunities in the human liver models market. Upgrades in the technology and inventions in the field are propelling the human liver model market.
On the other hand, expert professionals are lacking and this has been a major challenge faced by the human liver models market all over the world.
New product launches and acquisitions to flourish the market:
On February 13th, 2018, Wake Forest Institute for Regenerative Medicine (WFIRM) developed highly sophisticated and up-to-date mini livers which will help the scientists in understanding and finding a treatment for the congenital liver diseases.
On May 27th, 2018, Ascendance Biotechnology has been acquired by BioIVT LLC which helped them develop into huge cell-based assay firms.
Surge in usage in Research Institutes applications:
Improvement and advances in the healthcare infrastructure and the rising cases of liver diseases in the world have been increasing the demand for the human liver model market. The presence of different
conventional pharmaceutical, biotechnology and life-science industries and spreading awareness for the various liver model technology.
Key benefits of the report:
- This study presents the analytical depiction of the global Human Liver Models industry along with the current trends and future estimations to determine the imminent investment pockets.
- The report presents information related to key drivers, restraints, and opportunities along with detailed analysis of the global Human Liver Models market share.
- The current market is quantitatively analyzed to highlight the global market growth scenario.
- Porter’s five forces analysis illustrates the potency of buyers & suppliers in the market.
- The report provides a detailed global Human Liver Models market analysis based on competitive intensity and how the competition will take shape in coming years.
Questions answered in the Human Liver Models Market research report:
- What are the leading market players active in the Human Liver Models market?
- What the current trends will influence the market in the next few years?
- What are the driving factors, restraints, and opportunities in the market?
- What are the projections for the future that would help in taking further strategic steps?
Human Liver Models Market Report Highlights
| Aspects | Details |
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 Key Market Players | Organovo Holdings Inc, Emulate Inc., BioIVT., Ascendance Bio, Bio Innovations, Cyfuse Biomedical, HìRELCN, Mimetas, InSphero |
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