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LI_161523
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Pages: 110
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Dec 2016 | 3548 Views
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Author(s) :
Sriram Radhakrishnan
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Tables: 7
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Charts: 7
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Global In Vitro Toxicity Testing(IVTT) Market was valued at $3,366 million in 2016, and is expected to reach $7,813 million by 2022, supported by a CAGR of 15.01% during the forecast period 2016 - 2022. In vitro is the process that helps examine harmful chemicals over the isolated part of the organism. It is used to identify hazardous chemical substances and helps detect the toxicity at early stages of the development of new products such as drugs, cosmetics, and food additives. The in vitro toxicity testing is mainly used for safety evaluation in drug development and also for ranking the chemicals according to their potency. The absorption, distribution, metabolism, excretion (ADME), dose response, threshold response of drug can also be determined by the in vitro toxicity testing.
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The global in vitro toxicity testing market is expected to witness notable growth during the analysis period due to the increase in number of R&D procedures, which require in vitro testing, ban on animal testing, and increase in awareness about the environmental concerns. In addition, advancement in genetics and genetic screening approaches and emergence of new approaches of 3D cell culture can boost the in vitro toxicity testing market. The large size companies have focused on new product launch to meet the specific requirements of the researchers.
In Vitro Toxicity Testing Market Segment Review
The report analyzes the in vitro toxicity testing market into three segments, namely: type, end users, and geography. By type, the market is segmented into absorption, toxic substances, and dose. Based on end users, the market is categorized into cosmetic and household products, pharmaceutical industry, food industry, and chemical industry. Based on geography, the in vitro toxicity testing market is categorized into North America, Europe, Asia-Pacific, and LAMEA.
At present, absorption segment has witnessed large-scale adoption of IVTT market. Toxic substances and dose screening are some of the other segments in the global IVTT market. These segments are anticipated to witness increase in market share due to increase in the demand for IVTT in pharmaceutical, chemicals, cosmetics, and household products. Moreover, stringent government regulations to reduce the cruelty while performing experiment on animals, increase global illicit drug abusers and enhanced efficiency of IVTT in diagnosis are some other driving factors of this market. However, decrease in adoption rate of IVTT and incapability of IVTT to detect toxicities due to autoimmunity and immunostimulation can hinder the market growth.
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The significant impacting factors include increase in demand for in vitro models as compared to in vivo models and screening of toxicity in early stages of drug development. Along with these factors, the market is influenced by the stringent government regulations towards the environment, increased global illicit drug abusers, enhanced efficiency of IVTT in cancer diagnosis, advancement in technologies of IVTT, and many others. However, each factor would have its definite impact on the market during the forecast period.
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The key players profiled in this report include Agilent Technologies, Inc., BioReliance, Inc., Alere, Inc., Charles River Laboratories International, Inc., General Electric Company, Covance, Inc., Catalent, Inc., Eurofins Scientific, Bio-Rad Laboratories, Inc., and Thermo Fisher Scientific, Inc. There are other players in the in vitro toxicity testing market, which include Cyprotex plc, Accelrys, Inc., Molecular Toxicology Inc., MatTek Corporation, Xenometrix AG, and Quest Diagnostics Incorporation.
The report provides an extensive analysis of the current trends and highlights the market potential from 2014 to 2022, in terms of value.
The market scenario is comprehensively analyzed with respect to the type and end users.
Comprehensive analysis of the patents is provided to determine the prevailing opportunities.
Recent developments, key manufacturers, and market shares are listed in this report to analyze the competitive scenario of the market.
In-depth analysis of the market based on geography gives an understanding of the regional market, which assists in strategic business planning.
The global in vitro toxicity testing market segmentation is explained below:
Absorption
Toxic Substances
Dose
Cosmetics and Household Products
Pharmaceutical Industry
Food Industry
Chemical Industry
North America
Europe
Asia-Pacific
LAMEA
In vitro toxicity testing is used to identify hazardous chemical substances and helps detect the toxicity at early stages of the development of new products such as drugs, cosmetics, and food additives. The in vitro toxicity testing is mainly used for safety evaluation in drug development and also for ranking the chemicals according to their potency. The absorption, distribution, metabolism, excretion (ADME), dose response, and threshold response of the drug can also be determined by the in vitro toxicity testing.
The increase in rate of global illicit manufacture of drugs and supply of illicit drugs are expected to expand the global in vitro toxicity testing market. Europe is the lucrative market in the illicit drug abuse followed by North America (U.S.). To detect eye irritancy, the in vivo test known as Draize test is replaced by Bovine corneal opacity and permeability (BCOP) test and isolated Chicken eye method (in vitro test) and to detect skin irritancy and corrosivity, the classic Draize skin test (in vivo test) is replaced by EPISKIN and EpiDerm (in vitro test) which are approved by the European Centre for the Validation of Alternative Methods (ECVAM).
Increase in adoption of IVTT in food industry is expected to make food industry the fastest growing segment and is thus identified as one of the lucrative targets for investment. As compared to other segments, this segment possesses larger market size by value. Other emerging applications in the chemical industry are expected to witness good growth in the coming years. This is due to the introduction of advanced technologies and investment in new technologies in IVTT for detecting toxicity at the early stages of development.
Europe is the largest contributor in the in vitro toxicity testing market due to the improvement in technologies and increased R&D to detect toxicity followed by North America and then Asia-Pacific. India and China are expected to be the fast growing regions in the global in vitro toxicity testing market. Further advancements such as the limited production and sale of the animal tested cosmetics and promotion of the anti-animal testing laws are anticipated to expand the market growth of the global in vitro toxicity testing market.
Key players in the in vitro toxicity testing include Agilent technologies Alere (Covance Inc. Bio Rad Laboratories General Electric Company Eurofins Scientific, Sigma-Aldrich Co. Charles River Laboratories International, ThermoFisher Scientific Inc., and Catalent.
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