Long Read Sequencing is also referred to as third-generation sequencers, are used to directly sequence single molecules of DNA in real time. It is often carried out without the need for amplification. The method of direct sequencing allows the production of comparatively longer reads than those from Short Read Sequencing. It allows for the retrieval of longer sequence which is greater than (> 10,000 bp). Other ‘synthetic’ LRS approach uses modified sample processing and SRS to allow computationally reconstruct long reads from shorter sequencing tools. Long reads can develop de novo assembly, transcript isoform identification, detection of structural variants and mapping certainty. These competences, together with continuing improvement in throughput, accuracy, and cost reduction, have made long-read sequencing an option for a broad range of applications in genomics for both model and non-model organisms.
COVID-19 scenario analysis:
The outbreak of the pandemic led the government around the globe to constantly focus on investing on the development of the vaccines. The Long Read Sequencing can be used to innovate the vaccines or the medication required for the COVID-19 virus. Furthermore, during this situation about 115 vaccine candidates and 155 molecules are in the Research and Development pipeline. The demand for the management of covid-19 is surging due to the global death rates getting increased from the onset of the pandemic. There has been reduction in the production of the other drugs but the medication such as Hydrocholroquine rose at a higher rate, as it can be used in the management of COVID-19. Hence, the pharmaceutical industry and biotechnology industries are anticipated to experience a significant growth in the near future.
Top impacting factors: Market Scenario Analysis, Trends, Drivers and Impact Analysis
The rise in advancements in the technology of Long Red Sequencing as a third generation sequencing and the advantage of LGS over other methods would help the market surge in the coming years. There is a steep increase in the investments carried out by the major market players for the Research and development of the LGS technology which is expected to help the market gain maximum shares. Furthermore, there is a hike in the number persons experiencing genetic disorders where the LGS technology can be used as a therapeutic measure, which is expected to boost the industry in the coming years. The advantage of LGS being the reason that it is cost-efficient and real time data can be received, supporting the samples, which need to be fresh for analysis and those samples which are time-sensitive. The growth in the analysis of complicated genomic sequences would help the market boost in the near future. However, the factor which may hinder the growth of the industry include the higher quantity of the sample requisite for testing.
The global long red sequencing market trends are as follows:
New product launches to flourish the market
The major players are innovating new technologies to meet the demand posed by the market which would help the market gain greatest revenue in the forecast period. For instance, in May 2019, Longas, which is amongst the developer of the Next Generation Sequencing announced that it had launched Morphoseq. It is a technology which is designed to improvise the performance of industry-standard NGS platforms by increasing effective read lengths. It can convert short read sequencers into ‘virtual long read’ sequencers, empowering finished-quality genomic assemblies with higher accuracy, including resolution of difficult-to-assemble genomic regions.
Additionally, in July 2019, Loop Genomics launched four new Microbiome Kits to support their ability to perform long-reads on Illumina sequencers. The four kits are amongst low biomass phased V1-V9 full-length 16S kit with picogram input amounts and also zero Human DNA background, a phased 18S-ITS1-ITS2 long-read solution for ultra-high resolution fungal Mycobiome profiling that interrogates a ~2.5KB contiguous region of the genome and a 16S read-cloud kit which gives away a lower cost solution for labs in search of UMI-based Microbiome quantification with V1-V9 coverage, but without V1-V9 phasing.
Surge in incidences of genetic disorders would boost the market
The growth in the number of individuals facing genetic disorders would help in the growth of the market in the coming years. According to the data estimated by the Centers for Disease Control and Prevention, Sickel Cell Disease affects approximately 100,000 Americans. The growth in the patients would draw the attention of majority of the key players to bring up solutions and hence, is anticipated to propel the growth of the market in the near future.
Furthermore, according to the Centers of Disease Control and Prevention, the estimated number of individuals experiencing Down’s syndrome is growing rapidly. It is stated to be the most common chromosomal disorder. The estimates each year, is about 6,000 babies are born with Down syndrome, which is about 1 in every 700 babies born. The rise in the concern to experience better quality of life would help the market gain maximum shares.
Key benefits of the report:
- This study presents the analytical depiction of the global Long Red Sequencing industry along with the current trends and future estimations to determine the imminent investment pockets.
- The report presents information related to key drivers, restraints, and opportunities along with detailed analysis of the global Long Red Sequencing market share.
- The current market is quantitatively analyzed to highlight the global Long Red Sequencing market growth scenario.
- Porter’s five forces analysis illustrates the potency of buyers & suppliers in the Long Red Sequencing market.
- The report provides a detailed global Long Red Sequencing market analysis based on competitive intensity and how the competition will take shape in coming years.
Questions answered in the Long Red Sequencing Market research report:
- Which are the leading market players active in the Long Red Sequencing market?
- What are the current trends will influence the market in the next few years?
- What are the driving factors, restraints, and opportunities in the Long Red Sequencing market?
- What are the projections for the future that would help in tasking further strategic steps?
Long Red Sequencing Market Report Highlights
| Aspects | Details |
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 Key Market Players | NextOmics, Genome Transcriptome Facility of Bordeaux, Oxford Nanopore Technologies Limited, Institute of Integrative Biology of the Cell (I2BC), MicrobesNG, Future Genomics Technologies B.V, ., Takara Bio Inc, Quantapore, Inc, , Stratos Genomics Inc, BaseClear B.V |
 Other Players | Garvan Institute of Medical Research |
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