Lyophilization Equipment Market Overview:
The global lyophilization equipment market size was valued at $5015.2 million in 2020 and is projected to reach $10615.7 million by 2030 registering a CAGR of 7.80% from 2021 to 2030. Lyophilization involves freeze drying of products. In pharmaceutical industries, this process is widely used to increase the shelf-life of antibiotics, vaccines, and protein-based drugs. Biopharmaceutical companies are using lyophilization services to keep APIs and drugs sterile. Focus toward enhanced manufacturing practices is increasing the demand for lyophilization services.
Increase in demand for lyophilized products and preserved food drive the growth of the lyophilization equipment market. In addition, increase in production of protein-based drugs, injectable and biopharmaceuticals in biopharmaceutical companies that need the lyophilization equipment to give better stability, longer shelf life and broader range of temperature further fuel growth of the market. Furthermore, technological advancements in lyophilization equipment to enhance the scalability and quality of end products and reduce the time taken for the process are projected to further boost the growth of the market. However, growing utilization of alternative drying techniques in the pharmaceutical and biotechnology industries, high setup and maintenance cost of freeze-drying equipment and strict regulatory guidelines are expected to hinder growth of the market during the forecast period. In addition, lack of skilled workforce further hamper growth of the market. On the other hand, rise in the contract lyophilization and manufacturing services are expected to offer profitable opportunities for growth of the market during the forecast period.
The outbreak of COVID-19 has disrupted workflows in the healthcare sector around the world. The disease has forced a number of industries to shut down temporarily, including several sub-domains of health care. However, there has been a positive impact on some services including lyophilization equipment as lyophilization technique, which is used by researchers for Sars-CoV-2 virus vaccines such as mRNA-LNP SARS-CoV-2 vaccines to improve stability of vaccine.
Lyophilization is a powerful technique that is being employed by researchers as the scientific community strives to stabilize the Sars-CoV-2 virus vaccines such as mRNA-LNP SARS-CoV-2 vaccines to aid in the fight against the COVID-19 pandemic. For instance, according to an article published in National Library of Medicine in April 2021, as the presence of water initiates degradation reactions in mRNA-LNPs, lyophilization is expected to be a logical step to improve the long-term stability of mRNA-LNP formulations. The head of viral vaccines research at Pfizer, Philip Dormitzer, has already mentioned Pfizer’s aspiration to use lyophilization for mRNA-LNP SARS-CoV-2 vaccines (Dolgin, 2020). Moreover, a lyophilized form of an mRNA-based cytomegalovirus vaccine (mRNA-1647) is used in a phase 2 clinical trial. It has a claimed shelf life at 5 °C of ≥ 18 months. Hence, the outbreak of COVID-19 has positively impacted the lyophilization equipment market.
Lyophilization Equipment Market Segmentation
The global lyophilization equipment market is segmented on the basis of modality, scale of operation, application and region to provide a detailed assessment of the market. By modality, it is bifurcated into dryer and accessories. The dryer includes tray-style freeze dryers, manifold freeze dryers, and rotary freeze dryers. In addition, accessories include vacuum systems, CIP (clean-in-place) systems, drying chamber, and other accessories include loading and unloading systems, control and monitoring system, freeze drying, trays/shelves, manifolds, and others. Based on scale of operation, it is segmented into industrial-scale, pilot-scale and laboratory-scale. By application, it is segmented into food processing and packaging, pharmaceutical and biotech manufacturing, medical applications, and others include surgical application, and others. Region wise, the market is analyzed across North America, Europe, Asia-Pacific, and LAMEA.
Segment Review
Based on modality, the market is segmented into dryer and accessories. The dryer includes tray-style freeze dryers, manifold freeze dryers, and rotary freeze dryers. In addition, accessories include vacuum systems, CIP (clean-in-place) systems, drying chamber, and other accessories include loading and unloading systems, control and monitoring system, freeze drying, trays/shelves, manifolds, and others. The accessories segment dominated the global lyophilization equipment market in 2020 and is expected to remain dominant throughout the forecast period, owing to factors such as increase in usage of lyophilization equipment accessories in pharmaceutical and biotech companies as well as food processing and packaging companies for manufacturing of lyophilized products.
By Modality
Accessories segment holds a dominant position in 2020 and would continue to maintain the lead over the forecast period.
Based on scale of operation, it is segmented into industrial-scale, pilot-scale and laboratory-scale. Industrial scale segment dominated the global market in 2020 and is anticipated to continue this trend during the forecast period. This is attributed to cost affordability and large volume drying in industrial scale. Furthermore, growing applications in industrial scale manufacturing in food and pharmaceuticals production and packaging for improved product life will stimulate the segment growth potential.
Based on application, it is classified into food processing and packaging, pharmaceutical and biotech manufacturing, medical applications, and others include surgical application, and others. The food processing and packaging held the largest lyophilization equipment market share in 2020 and is expected to remain dominant throughout the forecast period owing to, increase in applications of lyophilization as a preservation technique for food products, as it retains the nutritional value and flavor of the food. Food ingredients are also freeze-dried to increase their shelf life, which is further propelling the use of this technology in food processing.
By Scale Of Operation
Industrial Scale segment is projected as one of the most lucrative segment.
Snapshot of the Asia-Pacific Lyophilization Equipment Market
Asia-Pacific offers profitable opportunities for key players operating in the lyophilization equipment market, thereby registering the fastest growth rate during the forecast period, owing to rising investments in emerging markets and growth in R&D expenditure and geographic expansion of lyophilization equipment companies in this region.
The key market players profiled in the report include Thermo Fisher Scientific, Inc., Azbil Telstar SL (Azbil Corporation), GEA Group, Millrock Technology Inc, Zirbus Technology GmbH, Harbour Group Industries (SP Industries), Biopharma Process Systems Ltd., LTE Scientific Ltd, Martin Christ Gefriertrocknungsanlagen GmbH, and Labconco Corporation.
By Region
Asia-Pacific is expected to experience growth at the highest rate, registering a CAGR of 9.00 % during the forecast period.
Key Benefits For Stakeholders
- The study provides an in-depth analysis of the global lyophilization equipment market along with the current trends and future estimations to explain the imminent investment pockets.
- A comprehensive analysis of the factors that drive and restrict the lyophilization equipment market growth is provided in the report.
- Comprehensive quantitative analysis of the industry from 2020 to 2028 is provided to enable the stakeholders to capitalize on the prevailing lyophilization equipment market opportunities.
- Extensive analysis of the key segments of the industry helps to understand the application and products of lyophilization equipment used across the globe.
- Key market players and their strategies have been analyzed to understand the competitive outlook of the lyophilization equipment market.
Key Market Segments
By Modality
- Dryer
- Tray-style Freeze Dryers
- Manifold Freeze Dryers
- Rotary Freeze Dryers
- Accessories
- Vacuum Systems
- CIP (Clean-in-place) Systems
- Drying Chamber
- Other Accessories
By Scale of Operation
- Industrial-scale
- Pilot-scale
- Laboratory-scale
By Application
- Food Processing and Packaging
- Pharmaceutical and Biotech Manufacturing
- Medical Applications
- Others
By Region
- North America
- U.S.
- Canada
- Mexico
- Europe
- Germany
- France
- UK
- Italy
- Spain
- Rest of Europe
- Asia-Pacific
- Japan
- China
- Australia
- India
- South Korea
- Rest of Asia-Pacific
- LAMEA
- Brazil
- Saudi Arabia
- South Africa
- Rest of LAMEA
Lyophilization Equipment Market Report Highlights
| Aspects | Details |
 By MODALITY |
|
 By SCALE OF OPERATION |
|
 By APPLICATIONS |
|
 By Region |
|
 Key Market Players | AZBIL CORPORATION (AZBIL TELSTAR SL), BIOPHARMA PROCESS SYSTEMS LTD., .ZIRBUS TECHNOLOGY GMBH, GEA GROUP, LTE SCIENTIFIC LTD, THERMO FISHER SCIENTIFIC, INC., LABCONCO CORPORATION, MARTIN CHRIST GEFRIERTROCKNUNGSANLAGEN GMBH, MILLROCK TECHNOLOGY INC, HARBOUR GROUP INDUSTRIES (SP INDUSTRIES) |
Analyst Review
Lyophilization refers to the process of water removal that is particularly utilized in the preservation of perishable products. The purpose of the process is to prolong the shelf life of the products or to render the product more suitable for transport.
The increase in demand for lyophilization products, technological advancements in lyophilization equipment and rise in production of protein-based drugs, injectable and biopharmaceuticals in biopharmaceutical that need the lyophilization equipment to give better stability, longer shelf life and broader range of temperature are expected to propel growth of the lyophilization equipment market during the forecast period. Moreover, rise in the contract lyophilization and manufacturing services are expected to offer profitable opportunities for growth of the market during the forecast period. However, increasing utilization of alternative drying techniques in the pharmaceutical and biotechnology industries, high setup and maintenance cost of freeze-drying equipment, strict regulatory guidelines and lack of skilled personnel are expected to obstruct the market growth.
The accessories segment is expected to remain dominant during the forecast period, owing to increase in usage of lyophilization equipment accessories in pharmaceutical and biotech companies as well as food processing and packaging companies for manufacturing of lyophilized products. Moreover, Asia-pacific are expected to offer lucrative opportunities to the market during the forecast period, due to rising investments in emerging markets and growth in R&D expenditure and geographic expansion of lyophilization equipment companies in this region.
The total market value of lyophilization equipment market is $5015.2 million in 2020.
The forcast period for lyophilization equipment market is 2021 to 2030
The market value of lyophilization equipment market in 2021 is $5381.3 million.
The base year is 2020 in lyophilization equipment market
Top companies such as Thermo Fisher Scientific, GEA Group, Azbil Corporation, Harbour Group Industries, Martin Christ, and Labconco Corporation held a high market position in 2020.
Accessories segment is the most influencing segment owing to increase in usage of lyophilization equipment accessories in pharmaceutical and biotech companies as well as food processing and packaging companies for manufacturing of lyophilized products.
Increase in demand for lyophilization products, technological advancements in lyophilization equipment and rise in production of protein-based drugs, injectable and biopharmaceuticals in biopharmaceutical companies that need the lyophilization equipment to give better stability, longer shelf life and broader range of temperature are expected to propel growth of the lyophilization equipment market during the forecast period.
Asia-Pacific is expected to experience the highest growth rate during the forecast period, owing to rising investments in emerging markets and growth in R&D expenditure and geographic expansion of lyophilization equipment companies in this region.
Lyophilization equipment used in the process of water removal that is particularly utilized in the preservation of perishable products.
Lyophilization equipment prolong the shelf life of the products or to render the product more suitable for transport.
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