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Author(s): Male infertility Market Overview:
Male Infertility Market was valued at $216 million, and is expected to reach $301.5 million by 2020, supported by a CAGR of 5%. The inability of a couple to conceive within 12 months of unprotected intercourse is called infertility. According to National Institutes of Health in the U.S. there are approximately >2 million infertile couples of which about 40% accounts to male infertility. The most common type of male infertility is the idiopathic infertility and infertility due to varicocele. The basic treatments involved in male infertility are surgery, treatment for problems in intercourse, hormone treatment and ART technology.
There is a steady increase in the global infertility rates both in the developed and developing nations. The changing life style, delayed pregnancy and aging are few of the factors driving the global infertility cases. The report excludes basic male infertility treatments such as surgery, treatment for problems in intercourse and hormonal treatment. The report focuses on male infertility and its treatment techniques with focus on drugs and devices. There are various techniques that are used in the diagnosis of the male infertility such as DNA fragmentation, oxidative stress, CASA (computer assisted semen analysis), sperm penetration assay, sperm agglutination and microscopic examination. The DNA fragmentation is an emerging technique which has already gained popularity and is accepted as a routine technique in the developed countries. The technique is yet to gain popularity in the developing regions and yet to be used as a routine technique due to the cost hindrance.
Types of male disorders, 2015 (%)
The couple’s inability to conceive within one year of unprotected intercourse is defined as infertility. Approximately 15% of couples in North America and Europe in a given year are unable to conceive.
Fertility depends on male, female and both male and female factors. Among the infertility cases, 8% cases are due to male factors, 37% cases are due to female factors, 35% cases are both female and male factors and 5% cases are unexplained factors in both the genders.
Causes of male infertility
Fertility in male is defined as the normal functioning of the pituitary gland, hypothalamus and testes. Thus, various conditions can lead to infertility:
- 1-2% of the cases are due to problems in the hypothalamus
- 10-20% of the cases are due to blockage of the sperm pathway
- 30-40% of the cases are due to improper functions of the testes
- 40%-50% of the cases are unidentifiable
Evaluation of male infertility
An evaluation is done by studying the patient’s health and medical history. Physical examination comes under the evaluation tests which includes the measurement of weight, height, muscle distribution, assessment of body fat, visual observation of breasts and genitals and inspection of hair pattern and skin. For example, in cases of testosterone deficiency, there is loss of body and facial hair with decrease in testis size. The various other conditions that affect fertility are absence of vas deferens, varicocele and epididymis thickening.
The semen analysis technique is done to check the fertility level of the collected semen sample and to identify the reasons for infertility. The various techniques used in semen analysis are
DNA fragmentation
Oxidative stress analysis
Sperm penetration assay
Sperm agglutination assay
Computer assisted semen analysis (CASA)
Sperm agglutination
Microscopic examination
Others (biochemical assessment tests)
The DNA fragmentation technique and oxidative stress analysis test has a significant usage in the semen analysis technique. The DNA fragmentation test is expected to be the most widely used in the routine semen analysis test, when compared to the oxidative stress analysis test. This is due to DNA fragmentation test’s ability to measure DNA damage example SCSA (Sperm chromatin structure assay) a method used in DNA fragmentation testing, is a sensitive one and can measure DNA damage in 20% of couples with unexplained infertility. The oxidative stress analysis is not widely used as DNA fragmentation due to the alternative methods such as IVF/ICSI, for achieving pregnancy. The microscopic examination test is a routine mandatory test used in all cases, but the test is expected to be replaced by the CASA due to its automation.
Conventional, current and advanced treatments for male infertility
KEY BENEFITS
- The report provides detailed analysis about the driving and limiting factors of the male infertility market, which would give a deeper understanding of the subject and help in taking actionable decisions.
- The market size of the male infertility diagnostic and treatments will help in analyzing the market, thus helping the stakeholders understand opportunities in the male infertility market
- Market share analysis of both male and female infertility treatments that allow the decision makers to gauge the market strength and make profitable investments
- The report analyzes the market condition in a comprehensive and quantitative manner and forecast market trends and techniques used in male infertility treatments
Reason for the Study
- To study the various techniques used to treat male infertility
- To identify the benefits of the new techniques over the conventional techniques
- To study the treatment trends in various geographic regions
MALE INFERTILITY MARKET KEY SEGMENTS
The global male infertility market is segmented based on techniques and geography.
- MARKET BY TECHNIQUES
- DNA Fragmentation Technique
- Oxidative Stress Analysis
- Microscopic Examination
- Sperm Penetration Assay
- Sperm Agglutination
- Computer Assisted Semen Analysis
- Others
- MARKET BY GEOGRAPHY
- North America
- Europe
- Asia Pacific
- RoW
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