Report Code: A13363 | Nov 2023 | Pages: NA | ||
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Pandemic disrupted the entire world and affected many industries.
Get detailed COVID-19 impact analysis on the Neoantigen Market
Request Now !Neoantigen is a protein that forms on the cancerous cells as a result on mutations in the tumorous DNA. They are thus used in development on vaccines and immunotherapies against cancer cells. Neoantigens are recognized in the body by neoantigen-specific T cell receptors (TCRs). Neoantigen-based vaccines and target therapies have shown promising results in various clinical trials, owing to the fact that they can be recognized as non-self/foreign and germline by the host’s immune system. Neoantigens find huge significance in cancer immunoediting. It is a technique used to establish dual roles of immune system with respect to tumor growth. Several studies have postulated the fact that neoantigen immunotherapy can in fact aid in controlling tumor outgrowth, facilitate cellular transformation and share immunogenicity of tumors. Furthermore, neoantigens can be divided into personalized neoantigens and shared neoantigens. Shared neoantigens are not present specifically in regards to individualized genome while personalized neontigens are targeted on specific individuals. Prediction on the number of neoantigens present involves a well thought validated algorithms to select more reliable neoepitopes. The procedure for development of neoantigen cancer vaccine involves obtaining tumorous tissues from the patient and subsequently identifying mutant genes of the tumor. Post this, RNA/DNA sequent test is carried out to select appropriate mutated antigens. Finally, these mutated antigens are designed into suitable vaccines.
COVID-19 Impact Analysis
Pharmaceutical and biotech companies together with governments around the globe are working to address the COVID-19 outbreak, from supporting the development of vaccines to planning for medicine supply chain challenges. Currently, around 115 vaccine candidates and 155 molecules are in the R&D pipeline. Moreover, commonly used drugs such as hydroxychloroquine have witnessed a dramatic surge in demand for the management of COVID-19. Such high demand for these drugs has presented huge opportunities for manufacturers of COVID-19 management drugs, as many developed countries are facing shortage of these drugs. Thus, the pharmaceutical and biotechnology industries are expected to witness a significant growth in the future, owing to the demand for vaccine and treatment drugs for COVID-19. This, in turn, is expected to have a significant impact on the global neoantigens market.
Top Impacting Factors
Key Market Trends
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Neoantigen Market Report Highlights
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By Therapeutic Specialty |
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By Product |
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By Cell |
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By Treatment |
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By Technology |
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By Route of Administration |
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By Delivery Mechanism |
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Key Market Players | Moderna, Inc., Merck & Co. Inc, Gradalis, Inc., Genocea, Ziopharm Oncology, Inc., Achilles Therapeutics plc, Gritstone Oncology, Advaxis, Inc., Frame Cancer Therapeutics, Immunicum AB, Medigene AG |
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