Next Generation Sequencing Market

Next Generation Sequencing Market Overview:

The global next generation sequencing market size accounted for $6,598.62 million in 2020, and is projected to reach $35,503.66 million by 2030, registering a CAGR of 18.2% from 2021 to 2030. Next generation sequencing (NGS) is a massively parallel sequencing technology, which offers scalability, ultra-high throughput, and high speed to determine the order of nucleotides in entire genome. DNA pre-sequencing is one of the most significant steps in the overall sequencing protocol as it involves preparation of sample for the subsequent sequencing reaction. NGS is steadily being integrated into clinical laboratory analysis, testing, and diseases diagnostics in healthcare sectors, globally. NGS has been widely used in pharmacogenomics to accelerate the drug discovery process. 

Growth of the global next generation sequencing market is majorly driven by increase in genome mapping programs; rise in applications of next generation sequencing; increase in healthcare expenditure; and technological advancements in sequencing platforms. For instance, in 2019, Thermo Fisher Scientific, a world leader in serving science, launched Ion Torrent Genexus System which is a next generation platform that deliver the specimen to report in just a single day. Moreover, in 2019, Agilent Technologies, Inc., an American analytical development and manufacturing company, launched Magnis NGS Prep System, a next generation sequencing library preparation system which is designed to run the complex sequencing assays in a press of a button. The genetic make-up and configuration of the fetus can be detected through NGS-oriented tests such as non-invasive prenatal testing (NIPT), and pre-implantation genetic testing (PGT). The R&D related to NGS has been escalating to new heights through greater investment in NGS technologies throughout the world. Surge in demand for genome mapping program and rise in application of NGS boosts the growth of the market. 

However, lack of skilled professionals, and ethical and legal limitation associated with NGS are expected to restrict the market growth during the forecast period.

Next Generation Sequencing Market Segmentation

The next generation sequencing market is segmented on the basis of product, application, technology, end user, and region. By product, the market is categorized into consumables, platforms, and services. On the basis of consumables, it is further classified based on sample preparation consumables and other consumables. The sample preparation consumables are further segmented into DNA fragmentation, end repair, A-Tailing & size selection, library preparation & target enrichment, and quality control. By platforms, the market is divided into HiSeq, MiSeq, Ion Torrent, SOLiD, Pacbio Rs II & Sequel System, and other sequencing platforms. By service, it is divided into sequencing services and data management. The sequencing services are further segmented into RNA sequencing, whole exome sequencing, whole genome sequencing, targeted sequencing, chip sequencing, De novo sequencing and methyl sequencing. The data management services are further segmented into NGS Data analysis services, NGS data analysis software & workbenches, and NGS storage, management and cloud computing solutions.

On the basic of application, the next generation sequencing market is divided into diagnostics, biomarkers & cancer, reproductive health, personalized medicine, agriculture & animal research, and other applications. By technology, the market is categorized into sequencing by synthesis, ion semiconductor sequencing, sequencing by ligation, pyrosequencing, single molecule real time sequencing, and other technologies. By end user, the market is categorized into academic and research centers, pharmaceutical and biotechnology companies, hospitals and clinics, and other end users.

Region wise, the market is analyzed across North America (the U.S., Canada and Mexico), Europe (Germany, France, the UK, Italy, Spain, and rest of Europe), Asia-Pacific (Japan, China, India, Australia, South Korea, Taiwan, and rest of Asia-Pacific), and LAMEA (Brazil, Turkey, Saudi Arabia, South Africa, and rest of LAMEA). 

Segment review

Depending on product, the consumables segment dominated the market in 2020, and is expected to continue this trend throughout the forecast period, owing to development of technology in molecular genetics and surge in demand for novel pre-sequencing products and kits that execute DNA fragmentation, target enrichment, size selection, and others. However, the services segment is expected to witness considerable next generation sequencing market growth during the forecast period, due to advancement in technology based on SMRT sequencing, and increase in application of cloud computing for NGS data storage.

On the basis of application, the biomarker and cancer segment dominated the market in 2020, and is expected to continue this trend throughout the forecast period, due to increase in prevalence of cancer and advancement in technology in next generation sequencing. However, the personalized medicine segment is expected to witness considerable next generation sequencing market growth during the forecast period, due to surge in demand for drug treatment, advancement in R&D in healthcare sector, and rise in awareness for NGS testing in pharmaceutical and biotechnological industry.

On the basis of end user, the academic & clinical research centers segment dominated the market in 2020, and is expected to continue this trend throughout the forecast period, due to increase in application-based usage in these institutes and rise in oncology research. However, the pharmaceutical & biotechnology companies’ segment is expected to witness considerable market growth during the forecast period, due to increase in prevalence of chronic disease, and advancement in R&D in the next generation sequencing market for therapeutics, oncology, and genomics research.

North America accounted for a major share in the next generation sequencing market in 2020, and is expected to maintain its dominance during the forecast period, owing to technological advancements in sequencing platforms and increase in applications of NGS in this region. However, Asia-Pacific is expected to register highest CAGR of 19.0% from 2021 to 2030, due to increase in demand for NGS along with surge in awareness about NGS.

Key players operating in the global next generation sequencing market include Agilent Technologies, Inc., BGI Group, F. Hoffmann-La Roche AG, Illumina Inc, Precigen Inc., (Intrexon Bioinformatics Germany GmbH), Pacific Biosciences of California, Inc., PerkinElmer, Inc., PierianDx Inc., Qiagen N.V., and Thermo Fisher Scientific Inc.

Key Benefits For Stakeholders

• The study provides an in-depth analysis of the next generation sequencing market, and the current trends and future estimations to elucidate imminent investment pockets.
• It presents a quantitative analysis of the market from 2021 to 2030 to enable stakeholders to capitalize on the prevailing next generation sequencing market opportunities.
• Extensive analysis of the market based on procedures and services assists to understand the trends in the industry.
• Key players and their strategies are thoroughly analyzed to understand the competitive outlook of the next generation sequencing market.

Key Market Segments

By Product

• Consumables
  • Sample Preparation Consumables
    • DNA Fragmentation, End Repair, A-Tailing and Size Selection
    • Library Preparation & Target Enrichment
    • Quality Control
• Other Consumables
  • Platforms
  • HiSeq
  • MiSeq
  • Ion Torrent
  • SOLiD
  • Pacbio Rs II and Sequel System
  • Other Sequencing Platforms
• Services
  • Sequencing Services
    • RNA Sequencing
    • Whole Exome Sequencing
    • Whole Genome Sequencing
    • Targeted Sequencing
    • Chip Sequencing
    • De Novo Sequencing
    • Methyl Sequencing
  • Data Management Services
    • NGS Data Analysis Services
    • NGS Data Analysis Software & Workbenches
    • NGS Storage, Management and Cloud Computing Solutions

By Application

• Diagnostics
• Biomarkers and Cancer
• Reproductive Health
• Personalized Medicine
• Agriculture and Animal Research
• Other Applications

By Technology

• Sequencing by Synthesis
• Ion Semiconductor Sequencing
• Sequencing by Ligation
• Pyrosequencing
• Single Molecule Real Time Sequencing
• Other Technologies

By End User

• Academic and Research Centers
• Pharmaceutical and Biotechnology Companies
• Hospitals and Clinics
• Other End Users

By Region

• North America
  • U.S.
  • Canada
  • Mexico
• Europe
  • Germany
  • France
  • UK
  • Italy
  • Spain
  • Rest of Europe
• Asia-Pacific
  • Japan
  • China
  • India
  • Australia
  • South Korea
  • Taiwan
  • Rest of Asia-Pacific
• LAMEA
  • Brazil
  • Turkey
  • Saudi Arabia
  • South Africa
  • Rest of LAMEA

Key Market Players 

• Agilent Technologies, Inc
• BGI Group 
• F. Hoffmann-La Roche AG 
• Illumina Inc
• Precigen Inc., (Intrexon Bioinformatics Germany GmbH)
• Pacific Biosciences of California, Inc
• PerkinElmer, Inc.
• PierianDx Inc.
• Qiagen N.V.
• Thermo Fisher Scientific Inc.