According to a new report published by Allied Market Research, titled, “Digital PCR Market," The digital PCR market size was valued at $508.82 million in 2020, and is estimated to reach $1,305.3 Billion by 2030, growing at a CAGR of 8.6% from 2021 to 2030. Digital polymerase chain reaction (dPCR) is a laboratory method used to make many copies of very tiny amounts of the specific DNA from a sample. PCR allows these pieces of DNA to be amplified so that they can be detected. In addition, it is used for absolute quantification and analysis of minority sequences.
Digital PCR enhances the sensitivity of real-time PCR and detects rare events such as single nucleotide mutations in a population of wild type sequences. With dPCR, a sample is partitioned so that individual nucleic acid molecules within the sample are localized and concentrated within many separate regions. After PCR amplification, nucleic acids may be quantified by counting the regions that contain PCR end product and positive reactions. PCR may be used to look for certain changes in a gene or chromosome, which may help find and diagnose a genetic condition or a disease, such as cancer. It may also be used to look at pieces of the DNA of certain bacteria, viruses, or other microorganisms to help diagnose an infection.
The dPCR system is utilized for various applications, such as to measure varying degrees of cancer mutations, for cancer biomarker studies & copy number variation. It is also used to detect rare DNA target copies & resolve copy number variation states with superior sensitivity & resolution. Moreover, the digital PCR system is also used for pathogen detection, to carry out next-generation sequencing, to conduct accurate quantification & qualification of NGS libraries without the use of a standard curve, for gene expression analysis and for food testing.
Depending on technology, the market is fragmented into droplet digital PCR (ddPCR), chip based digital PCR, and BEAMing digital PCR. The ddPCR segment was the major revenue contributor in 2020, owing to the fact that ddPCR technique provides a precise measure of DNA molecules through each drop. In addition, massive sample partitioning is a key aspect of the droplet digital PCR technique, which increases the demand. On the other side, demand for chip based digital PCR has also increased day by day, as it reduces the risk of cross contamination, which is further anticipated to boost the digital PCR market growth.
On the basis of product type, the market is categorized into digital PCR systems, consumables & reagents, and software & services. The software & services segment is projected to exhibit the fastest growth during the forecast period, as the software helps improve the efficiency of management of digital PCR data. Thus, there is an increase in the demand for these products, thereby propelling the digital PCR market trends.
The COVID-19 outbreak is anticipated to have a positive impact on the growth of the digital PCR market size as digital PCR tests are used for diagnosis of COVID-19 infection. The rise in prevalence of COVID-19 infection boosts the growth of market. For instance, according to world health organization (WHO) report, as of 19 December 2021, over 273 million cases and over 5.3 million deaths have been reported globally. In addition, increase in number of dedicated COVID-19 diagnostic centers further contributes in growth of digital PCR industry.
KEY FINDINGS OF STUDY
- On the basis of technology, the droplet digital PCR segment was the highest contributor to the digital PCR market share in 2020.
- Based on product type, digital PCR systems segment dominates the market in 2020
- Depending on application, clinical diagnostics segment was the highest contributor to the market in 2020.
- By end user, pharmaceuticals & biotechnology industries segment dominates the market in 2020.
- Region wise, North America garnered the largest revenue share in 2020, whereas Asia is anticipated to grow at the highest CAGR during the forecast period.
North America was the leading revenue contributor to the global digital polymerase chain reaction market in 2020, and is expected to remain dominant throughout the forecast period. This is attributed to its well-developed healthcare industry, presence of leading molecular diagnostics manufacturers in the region, and rise in number of patients using personalized medicines. However, Asia-Pacific is expected to grow at the highest CAGR of 10.6% during the forecast period, as it offers lucrative opportunities for molecular diagnostics players due to increase in number of patients suffering from chronic diseases and improvement in healthcare facilities in the region.