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Small active pharmaceutical ingredients (API) molecule is an organic component with low molecular weight. It is an active ingredient used in pharmaceuticals and biological procedures. In addition, API can be used as a combination in finished pharmaceutical products. Being a vital element, its requirement is high in the pharmaceutical industry. The molecule is effective in the diagnosis, treatment, and prevention of various diseases. Small molecules may be used as research tools to probe biological function as well as lead in the development of new therapeutic agents. Some can obstruct a specific function of a protein or interrupt protein-protein interactions.
The molecular value of the small API is approximately 900 Daltons and size on the order of 1 nm. Due to its low molecular weight, the body absorbs this active solution quickly.
COVID-19 Impact analysis
Pharmaceutical and biotech companies together with governments around the globe are working to address the COVID-19 outbreak, from supporting the development of vaccines to planning for medicine supply chain challenges. Currently, around 115 vaccine candidates and 155 molecules are in the R&D pipeline. Moreover, commonly used drugs such as hydroxychloroquine have witnessed a dramatic surge in demand for the management of COVID-19. Such high demand for these drugs has presented huge opportunities for manufacturers of COVID-19 management drugs, as many developed countries are facing shortage of these drugs. Thus, the pharmaceutical and biotechnology industry is expected to witness a significant growth in the future, owing to the demand for vaccine and treatment drugs for COVID-19. This, in turn, is expected to have a significant impact on the small molecule API market.
Top Impacting Factors
Market Trends
New product launches to flourish the market
In March 2019, GHO Capital, a European healthcare investor, acquired a majority stake in Sterling Pharma Solutions, a manufacturer of small molecule APIs.
In January 2019, Cambrex Corporation, a manufacturer of small molecule innovator and generic APIs, acquired Avista Pharma Solutions, a contract manufacturing organization from Ampersand Capital Partners. The acquisition is expected to provide Cambrex the access to its manufacturing facilities.
In November 2019, Novartis announced the acquisition of CellforCure—a France-based CDMO—for producing molecules in-house, which was earlier contracted to CellforCure. These initiatives undertaken by key players are anticipated to boost the market growth.
In January 2020, Merck announced its strategic collaboration for the oncology platform with Taiho Pharmaceutical Co, Ltd. and Taiho Pharmaceutical Co., Ltd. to expand its focus on small molecule inhibitors for cancer research.
Key Benefits of the Report
Questions answered in the Small Molecule API Report
Small Molecule API Market Report Highlights
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Key Market Players | Teva Pharmaceutical Industries Ltd., AstraZeneca Plc., Cambrex Corporation, Pfizer, Inc., Baxter International Inc., Boehringer Ingelheim International GmbH, Celgene Corporation, BASF SE, Sanofi S.A., Sun Pharmaceutical Industries Ltd. |
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