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Spine Biologics Market

Spine Biologics Market Size, Share, Competitive Landscape and Trend Analysis Report by Product (Spinal Allografts, Bone Graft Substitutes, and Cell Based Matrix) and Surgery (Open Spine Surgery and Minimally Invasive Spine Surgery) - Global Opportunity Analysis and Industry Forecast, 2014-2022

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Author's: Deepa Tatkare | Roshan Deshmukh
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Spine Biologics Market Overview:

Global spine biologics market generated revenue of $1,644 million in 2015, and is projected to reach $2,214 million by 2022, growing at a CAGR of 4.3% during the forecast period. Spine biologics are used during spine fusion surgery for the treatment of spinal deformities such as trauma, tumors, degenerative disc disease, and spinal cord injuries. Increase in geriatric population, advantages of biologics such as minimal postoperative time, faster recovery, and their ability to activate cellular growth are the factors that drive the market growth. However, unfavorable reimbursement scenario, higher cost of the bone grafts, and certain ethical issues related to bone grafting procedures are expected to restrain the growth of the market.

Biologics are used during spinal fusion procedure, as they stimulate bone growth formation through inflammatory stage, repair stage, and remodeling stage. Therefore, rise in number of spinal fusion surgery boosts the use of biologics.

Increase in geriatric population is the major factor anticipated to fuel the demand for biologics in future. For instance, spinal disorders such as spinal stenosis is the most common problem in men and women over 50 years. Aging leads to structural alterations in spine such as thickening of the band of the tissue that supports the spine and enlargement of bones & joints, thus resulting in spinal impairment. According to “Eurostat”, the population of the European Union (EU) was estimated to be 508.5 million on January 1, 2015. Aged population (65 or over) had a share of 18.9%, which showed an increase of 0.4% compared to the previous year. Therefore, older people who are at a higher risk to develop spinal deformities have increased chances to undergo spinal fusion surgery, which in turn is projected to increase the demand for spine biologics.

South Africa: Spine Biologics Market ($Million), 2014-2022

South Africa: Spine Biologics Market ($Million), 2014-2022

On the basis of product type, spine biologics is segmented into spine allografts, bone graft substitutes, and cell-based matrices. The emergence of biologic materials is one of the recent developments of spine fusion surgery. Earlier autografts were considered as the primary bone graft choice; however, owing to various complications related to it such as pain, infection, and weakened bone, allograft evolved as a better treatment option. Presently, bone morphogenetic proteins, bone grafts, and cell-based matrix are used as biologics options. Thus, with continuous development of new products, the use of biologics in spine surgeries is expected to witness a higher demand in the future.


Spine Biologics Market Segmentation

The key companies that operate in the spine biologics market are Alphatec Holdings, Inc., Depuy Synthes (Johnson & Johnson), Exactech, Inc., Globus Medical, Inc., Medtronic plc, NuVasive, Inc., Orthofix International N.V., RTI Surgical, Inc., SeaSpine, and Zimmer Biomet Holdings, Inc. Other players include Life Spine, Inc., Nutech, and XTANT MEDICAL.

Key Benefits of the Report

  • The study provides an in-depth analysis of the global spine biologics market with current trends and future estimations to elucidate the imminent investment pockets.
  • Quantitative analysis from 2014 to 2022 is expected to enable the stakeholders to capitalize on prevailing market opportunities.
  • The report provides actual historical figures for 2014 and Y-o-Y forecasts from 2016 to 2022, considering 2015 as base.
  • Comprehensive analysis of all geographic regions is provided to determine the prevailing opportunities in these geographies.
  • Extensive analysis is conducted by closely following key product positioning and monitoring the top contenders within the market framework.

Spine Biologics Market Key Segments

By Product

  • Spinal Allografts
    • Machined Bones Allograft
    • Demineralized Bone Matrix
  • Bone Graft Substitutes
    • Bone Morphogenetic Proteins
    • Synthetic Bone Grafts
  • Cell based Matrix

By Surgery

  • Open Spine Surgery
  • Minimally Invasive Spine Surgery

By Geography

  • North America
    • U.S.
    • Canada
    • Mexico
  • Europe
    • France
    • Germany
    • UK
    • Spain
    • Italy
    • Rest of Europe
  • Asia-Pacific
    • Japan
    • China
    • Australia
    • India
    • South Korea
    • Rest of Asia-Pacific
    • Brazil
    • Saudi Arabia
    • South Africa
    • Rest of LAMEA

Spine Biologics Market Report Highlights

Aspects Details
Spine Biologics Market- Global Opportunity Analysis and Industry Forecast, 2014-2022 By PRODUCT
  • Spinal Allografts
    • Machined Bones Allograft
    • Demineralized Bone Matrix
  • Bone Graft Substitutes
    • Bone Morphogenetic Proteins
    • Synthetic Bone Grafts
  • Cell based Matrix
Spine Biologics Market- Global Opportunity Analysis and Industry Forecast, 2014-2022 By SURGERY
  • Open Spine Surgery
  • Minimally Invasive Spine Surgery
Spine Biologics Market- Global Opportunity Analysis and Industry Forecast, 2014-2022 By Region
By Region
  • North America  (U.S., Canada, Mexico)
  • Europe  (France, Germany, Italy, Spain, UK, Russia, Rest of Europe)
  • Asia-Pacific  (China, Japan, India, South Korea, Australia, Thailand, Malaysia, Indonesia, Rest of Asia-Pacific)
  • LAMEA  (Brazil, South Africa, Saudi Arabia, UAE, Argentina, Rest of LAMEA)
Key Market Players
Key Market Players


Analyst Review

Spinal disorders such as spinal stenosis, spondylolisthesis, and scoliosis constitute a major proportion of health and economic burden, hence usage of effective spine biologics during spine surgery becomes a vital need for the treatment of the spinal disorders. To alleviate the aforementioned spine-related disorders and improve patient’s quality of life, spinal surgery is emerging as an ideal treatment option. Thus, rise in demand for spine surgery consequently drives the growth of spine biologics market, as biologics are widely adopted to promote fusion healing, which pedicle screws and rods are unable to provide.

Increase in incidences of spine-related disorders such as stenosis has led to the increase in the adoption of the spinal biologics. In addition, elimination of the need to harvest bone from the patient’s body in a secondary procedure, stimulation of the process of bone growth in spinal fusion surgery, shorter operating times, and reduced hospital stays fuel the growth of the market globally.

Advent of spine surgery treatment is one of the major factors that boosts the market growth. For instance, most of the spine surgeons these days prefer minimal invasive surgical techniques for a wide range of spine fusion procedures, which further use spine biologics. This is attributed to minor complications associated with the procedure such as reduced length of hospital stays and less bleeding.

Geographically, Asia-Pacific offers lucrative growth opportunity for the market due to growth in healthcare expenditure, increase in geriatric population, and rise in incidence of spine impairments. Thus, emerging economies (such as China & India) possess high potential for the market growth in spine biologics.

Author Name(s) : Deepa Tatkare | Roshan Deshmukh

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Spine Biologics Market

Global Opportunity Analysis and Industry Forecast, 2014-2022