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2024

Urokinase Market

Urokinase Market Size, Share, Competitive Landscape and Trend Analysis Report, by Type, by End User : Global Opportunity Analysis and Industry Forecast, 2024-2033

LS : Healthcare

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Author's: Digvijay Gawali | Roshan Deshmukh
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Urokinase Market Research, 2033

The global urokinase market size was valued at $1.8 billion in 2023, and is projected to reach $3.1 billion by 2033, growing at a CAGR of 5.7% from 2024 to 2033. The urokinase market is driven by increasing incidences of cardiovascular diseases, particularly thrombosis, rising geriatric populations, advancements in biotechnology and greater investments in healthcare infrastructure is expected to contribute significantly in the market growth.

Urokinase Market  by Type

Market Introduction and Definition

Urokinase, also known as urokinase-type plasminogen activator (uPA) , is an enzyme that plays a critical role in the breakdown of blood clots (fibrinolysis) . Urokinase is a serine protease originally derived from human urine, but now commonly produced via recombinant DNA technology. Urokinase functions by converting plasminogen to plasmin, an enzyme that degrades fibrin, the main component of blood clots. Clinically, urokinase is used as a thrombolytic agent to treat conditions such as acute myocardial infarction (heart attack) , pulmonary embolism, and deep vein thrombosis by dissolving clots that obstruct blood flow. The drug is administered intravenously in a hospital setting under strict medical supervision due to the risk of bleeding complications. 

Key Takeaways 

  • The urokinase market share study covers 20 countries. The research includes a segment analysis of each country in terms of value for the projected period. 
  • More than 1, 500 product literatures, industry releases, annual reports, and other such documents of major urokinase industry participants along with authentic industry journals, trade associations' releases, and government websites have been reviewed for generating high-value industry insights.
  • The study integrated high-quality data, professional opinions and analysis, and critical independent perspectives. The research approach is intended to provide a balanced view of global markets and to assist stakeholders in making educated decisions in order to achieve their most ambitious growth objectives

Key Market Dynamics

According to urokinase market trends analysis, key factors driving the market growth are rise in geriatric population, surge in prevalence of cardiac disorders, high research and development activities on urokinase. The increasing geriatric population is a significant driver for the growth of the urokinase market. According to World Health Organization, by 2050, 22% of the global population will be aged above 60 years. As the global population ages, the prevalence of various age-related health conditions, including cardiovascular diseases, deep vein thrombosis, and pulmonary embolism, rises correspondingly. These conditions often require thrombolytic therapy, for which urokinase, an enzyme used to dissolve blood clots, is a key treatment. Elderly individuals are particularly susceptible to these diseases resulting in the rise in demand for effective thrombolytic agents like urokinase. Thus, the rise in geriatric population is expected to significantly contribute in the urokinase market growth.

In addition, according to the urokinase market forecast analysis, research and development on the urokinase to explore its therapeutic and diagnostic uses is expected to drive the growth of the market. In an article published by National Library of Medicine in 2022, it was reported that Urokinase-type plasminogen activator receptor (uPAR) is an attractive target for the treatment of cancer, because it is expressed at low levels in healthy tissues but at high levels in malignant tumors. This selective expression makes urokinase-type plasminogen activator receptor an ideal candidate for targeted cancer therapies, minimizing damage to healthy tissues while effectively attacking cancerous cells. Thus, the research and development on the urokinase to explore its therapeutic and diagnostic uses is expected to contribute significantly to the growth of the urokinase market size.

Global Heart & Circulatory Disease Prevalence

The growing prevalence of heart and circulatory diseases is a significant global health concern, driven by factors such as aging populations, sedentary lifestyles, poor dietary habits, and rising rates of obesity and diabetes. Cardiovascular diseases (CVDs) , including heart attacks, strokes, and peripheral artery diseases, are leading causes of morbidity and mortality worldwide. As the incidence of these conditions increases, there is a corresponding rise in the demand for effective treatments and interventions. One such intervention is the use of thrombolytic agents like urokinase, which dissolves blood clots and restores normal blood flow in patients experiencing acute myocardial infarctions or other thromboembolic events.

According to urokinase market opportunity analysis growing burden of cardiovascular diseases is expected to significantly impact the growth of the urokinase market. As healthcare systems and providers seek to manage and treat an increasing number of patients with thrombotic complications, the demand for urokinase is expected to rise. Advancement in medical technology and an expanding understanding of the benefits of early thrombolytic therapy further contribute in market growth. Additionally, the increasing focus on improving patient outcomes and reducing healthcare costs through effective management of heart and circulatory diseases is expected to drive the adoption of urokinase.

Urokinase Market by

Market Segmentation

The urokinase industry segmented into by type, end user, and region. By type, the market is divided into urokinase powder, urokinase solution. By end user, the market is divided into hospitals, and clinics. Region wise, the market is analyzed across North America, Europe, Asia-Pacific, and LAMEA.

Regional/Country Market Outlook

North America dominated the urokinase market share in 20023 owing to well-established healthcare infrastructure, high prevalence of cardiovascular diseases, and robust research and development activities, and strong presence of major key players. However, according to urokinase market analysis, Asia-Pacific region is witnessing rapid growth propelled by increasing healthcare expenditure, a rising geriatric population, and developing healthcare infrastructure and pharmaceutical industry.

  • According to 2024 article by British Heart Foundation, 7.6 million people are living in with heart and circulatory disease in UK.  As urokinase is a crucial part of circulatory disease management, the rise in the prevalence of circulatory disease is expected to drive the demand of urokinase.
  • In the 2023 edition of the Journal for Clinical Diagnosis and Research, it as reported that acute myocardial infarction accounted for over 25% of all deaths occurred due to cardiovascular diseases. The rise in awareness about the sevearity of the cardiovascular diseases and increasing healthcare access is expected to drive the demand of the urokinase.

Industry Trends

  • In a 2023 article published by National Library of Medicine, around 3 million people worldwide suffer from acute myocardial infarction. Urokinase plays a crucial role in the acute phase of myocardial infarction, where timely reperfusion is crucial for protecting the myocardium. Thus, the rise in the prevalence of myocardial infarction is expected to drive the growth of the market.
  • In a 2023 article published by National Library of Medicine, it was reported that urokinase can be effectively used to treat tuberculosis. Urokinase can increase total pleural effusion, decrease residual pleural thickness, improve the pulmonary function, and shorten the time of pleural effusion absorption. Thus, research and development to evaluate pharmacological effectivity of urokinase in for treatment various diseases is expected to contribute significantly to growing adoption of the urokinase.
  • According to American Heart Association, in 2021, coronary heart disease (CHD) was the leading cause of deaths in U.S., accounting for 40.3% death. Since, the urokinase plays crucial role in managing cardiac conditions such as coronary heart disease. Thus, surge in prevalence of coronary heart disease is expected to drive the growth of the market

Competitive Landscape

The major players operating in the urokinase market include NDpharm, Wanhua Biochem, Jiangxi Haoran Bio-Pharma, Jiangsu Aidea Pharmaceutical, Techpool, Microbic Biosystems Inc, LIVZON, Cadila Healthcare Limited, TAJ Pharmaceuticals Limited, Microbix Biosystems Inc, Syner Medica LTD, and ImaRx Therapeutics, Inc.  Other players in Urokinase market includes Wilex AG, Abbott Laboratories, and Merck KGaA.

Key Sources Referred

  1. World Health Organization
  2. National Cancer Institute
  3. Center of Disease Control and Prevention.
  4. National Library of Medicine
  5. Indian Council of Medical Research
  6. Journal for Clinical Diagnosis and Research
  7. British Heart Foundation
  8. American Heart Association

Key Benefits for Stakeholders

  • This report provides a quantitative analysis of the market segments, current trends, estimations, and dynamics of the urokinase market  by type analysis from 2024 to 2033 to identify the prevailing urokinase market  by type opportunities.
  • The market research is offered along with information related to key drivers, restraints, and opportunities.
  • Porter's five forces analysis highlights the potency of buyers and suppliers to enable stakeholders make profit-oriented business decisions and strengthen their supplier-buyer network.
  • In-depth analysis of the urokinase market  by type segmentation assists to determine the prevailing market opportunities.
  • Major countries in each region are mapped according to their revenue contribution to the global market.
  • Market player positioning facilitates benchmarking and provides a clear understanding of the present position of the market players.
  • The report includes the analysis of the regional as well as global urokinase market  by type trends, key players, market segments, application areas, and market growth strategies.

Urokinase Market Report Highlights

Aspects Details
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Market Size By 2033

USD 3.1 Billion

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Growth Rate

CAGR of 5.7%

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Forecast period

2024 - 2033

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Report Pages

280

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By Type
  • Urokinase Powder
  • Urokinase Solution
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By End User
  • Hospital
  • Clinics
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By Region
  • North America  (U.S., Canada, Mexico)
  • Europe  (Germany, France, UK, Italy, Spain, Rest of Europe)
  • Asia-Pacific  (Japan, China, Australia, India, South Korea, Rest of Asia-Pacific)
  • LAMEA  (Brazil, Saudi Arabia, South Africa, Rest of LAMEA)
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Key Market Players

Livzon Pharmaceutical Group Inc., Jiangsu Aidea Pharmaceutical, Jiangxi Haoran Bio-Pharma, Wanhua Biochem, Cadila Healthcare Limited, Microbix Biosystems Inc, Microbic Biosystems Inc, TAJ Pharmaceuticals Limited, NDpharm, Techpool

Author Name(s) : Digvijay Gawali | Roshan Deshmukh
Frequently Asked Questions?

The forecast period for Urokinase Market is 2024-2033.

The global urokinase market size was valued at $1.8 billion in 2023

The global urokinase market size is projected to reach $3.1 Billion by 2033.

The base year is 2023 in Urokinase Market

Urokinase, also known as urokinase-type plasminogen activator (uPA), is an enzyme that plays a crucial role in the body's ability to break down blood clots. It is a serine protease, meaning it is an enzyme that cleaves peptide bonds in proteins, and is involved in the conversion of plasminogen to plasmin, the major enzyme responsible for clot breakdown.

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Urokinase Market

Global Opportunity Analysis and Industry Forecast, 2024-2033