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2021
Viral Vector Production Market

Viral Vector Production Market by Product Type (Retroviral Vector, Adenoviral Vector, Adeno-associated Viral Vector, and Other Viral Vectors), Disease (Cancers, Genetic Disorders, Infectious Diseases, and Other Diseases), Application (Gene Therapy and Vaccinology), and End User (Pharmaceutical & Biopharmaceutical Companies and Research Institutes): Global Opportunity Analysis and Industry Forecast, 2021–2030

A13615
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Dec 2021 | 119 Views
   
Author(s) : Onkar Sumant
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COVID-19

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Viral vectors are commonly used tools by molecular biologists delivering genetic materials into cells. The specialized molecular mechanisms are evolved by viruses for efficient transport of their genomes inside the cells that are infected by them with the process of transduction.

The viral vector manufacturing market has grown significantly, owing to the increasing need for advanced clinical treatments and growing emphasis given the evolving field of medical science further supported by transforming technologies. Viral vectors can be applied in gene therapy to treat different diseases such as heart defects, metabolic diseases, cancer, and neurodegenerative disorders. Being based on baculovirus, herpes simplex viruses, and adenoviruses, viral vectors are finding greater application in vaccinology and novel drug development. Vectors should be modified to provide safe handling (no production of new virions in a host) and low toxicity (no effect on the physiology of the normal host cell). They should further be stable (no rearrangement of the genome), and for manufacturing, it is important that the viral vector is easily quantified and that it lends itself to large-scale production.

Market Scope and Structure Analysis

Report Metric

Details

Market Size Available for Years

2020–2030

Base Year Considered

2020

Forecast Period

2021–2030

Forecast Unit

Value (USD)

Segments Covered

Product Type, Application, End User, and Region

Regions Covered

North America, Europe, Asia-Pacific, LAMEA

Companies Covered

Merck KGaA, Lonza, FUJIFILM Diosynth Biotechnologies U.S.A., Inc., Cobra Biologics Ltd., Thermo Fisher Scientific, Inc., Waisman Biomanufacturing, Genezen, YPOSKESI, Advanced BioScience Laboratories, Inc. (ABL, Inc.), Novasep Holding S.A.S, Orgenesis Biotech Israel Ltd. (formerly ATVIO Biotech Ltd.)


COVID-19 Impact analysis

The global market for viral vector production has benefited from the COVID-19 pandemic. Although viral vectors were widely employed for vaccine production before the introduction of COVID-19, the scientific community has had to repurpose existing methodologies due to the urgency of developing a vaccine against this virus. In the COVID-19 viral vector vaccines, non-replicating viral vectors are used. AstraZeneca and Janssen Pharmaceuticals have developed COVID-19 viral vector-based vaccines, in December 2020 and February 2021, respectively. Aside from these companies, many viral vector-based vaccines are now in development. As a result, demand for viral vectors has increased, resulting in increased revenue for viral vector manufacturers.

Top Impacting Factors

  • The growth of the viral vector production market is primarily being driven by the growing adoption of adenoviral vectors, lentiviral vectors, as well as retroviral vectors.
  • In addition, due to the growing incidence of various life-threatening diseases such as cancer, diabetes, hemophilia A, heart disease, and HIV, scientists are using viral vectors to develop curative therapies, thereby driving the market for viral vectors and plasmid DNA manufacturing.
  • The use of viral gene transfer vectors has increased due to the approval of therapies, the initiation of late-stage clinical trials for the treatment of genetic disorders, and the need for the prevention of infectious diseases through vaccination.
  • Moreover, initiatives such as ViroCell Biologics launching platforms for the clinical trial base manufacturing for addressing the bottlenecks associated with the viral vector supply chain amidst the COVID situation are attributive to drive manufacturing and research practices in viral vector academic organizations and CROs.
  • Increasing the introduction of advanced therapies along with the rising number of gene therapy-based R&D programs by companies are factors responsible for the market growth.
  • However, the transitioning of this niche industry to high manufacturing is one such factor that may restrain the growth of the market to a certain extent.

Market Trends

New product launches to flourish the market

In March 2021, the U.S. FDA approved ABECMA (idecabtagene vicleucel), a lentivirus-based gene therapy to treat R/R multiple myeloma. With the increasing gene therapy approvals and consequent increase in manufacturing capabilities, the competition in this arena is anticipated to intensify in the near future.

in April 2021, Albumedix extended research collaboration with Cobra Biologics for the upstream and downstream processing of AAV and lentiviral vector. Collaboration is intended for stability enhancement and process optimization.

In April 2020, Merck KGaA a leading science and technology company, announced that a 100 million facility, second in Carlsbad, California USA that is intended to boost its BioReliance viral and gene therapy service offering to help their customers to aid their customers to commercialize the gene therapies that are brought about by viral vectors concomitantly helping innovators scale up their production that is in tandem with the quantum that allows them to reach out to more patients.

Surge in usage due to chronic ailments

The development of therapies using viral vectors is in high demand due to the growing incidence of various life-threatening diseases such as diabetes, heart disease, HIV, cancer, and hemophilia A. Researchers are using viral vectors to develop curative therapies, as viral vectors are a promising tool for the development of vaccines and gene therapy.

According to the UNAIDS Statistics, in 2019, 38.0 million people were living with HIV and 1.7 million people became newly infected. According to the same source, 26 million people were taking antiretroviral therapy at the end of June 2020. In addition, recombinant viral vectors are highly efficient carriers of sequences encoding virus-disabling sequences. Thus, the rising prevalence of the chronic disease will lead to the expansion of the global viral vectors market.

Key Segments Covered

Segment

Subsegment

Product Type

  • Retroviral Vectors
  • Adenoviral Vectors
  • Adeno-associated Viral Vectors
  • Other Viral Vectors

By Disease

  • Cancers
  • Genetic Disorders
  • Infectious diseases
  • Other Diseases

Application

  • Gene Therapy
  • Vaccinology

End User

  • Pharmaceutical and Biopharmaceutical Companies
  • Research Institutes

Region

  • North America
    • U.S.
    • Canada
    • Mexico
  • Europe
    • Germany
    • France
    • UK
    • Italy
    • Spain
    • Rest of Europe
  • Asia-Pacific
    • China
    • Japan
    • India
    • South Korea
    • Australia
    • Rest of Asia-Pacific
  • LAMEA
    • Brazil
    • Saudi Arabia
    • South Africa
    • Rest of LAMEA


Key Benefits of the Report

  • This study presents the analytical depiction of the viral vector production along with the current trends and future estimations to determine the imminent investment pockets.
  • The report presents information related to key drivers, restraints, and opportunities along with detailed analysis of the viral vector production market share.
  • The current market is quantitatively analyzed from 2020 to 2030 to highlight the market growth scenario.
  • Porter’s five forces analysis illustrates the potency of buyers & suppliers in the market.
  • The report provides a detailed viral vector production market analysis depending on competitive intensity and how the competition will take shape in coming years.

Questions Answered in the Viral Vector Production Report

  • Who are the leading market players active in the viral vector production market?
  • What current trends will influence the market in the next few years?
  • What are the driving factors, restraints, and opportunities in the market?
  • What future projections would help in taking further strategic steps?
  • What is "viral vector production "?
  • What is "viral vector production " market prediction in the future?
  • Who are the leading global players in the "viral vector production " market?
  • What are the current trends and predicted trends?
  • What are the key benefits of the "viral vector production " market report?
 
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