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Acute Lymphocytic/Lymphoblastic Leukemia (ALL) Therapeutics Market by Drug (Hyper-CVAD Regimen, Linker Regimen, Nucleoside Metabolic Inhibitors, Targeted Drugs & Immunotherapy, CALGB 8811 Regimen, and Oncaspar), and Type (Pediatric and Adult): Global Opportunity Analysis and Industry Forecast, 2019–2026

LI_18564
Pages: 113
Jun 2019 | 3358 Views
 
Author(s) : Sagar Mukhekar & Snehal Manjrekar , Onkar Sumant
Tables: 50
Charts: 30
 

Acute Lymphocytic/lymphoblastic Leukemia Therapeutics Market Outlook - 2026

The global acute lymphocytic/lymphoblastic leukemia therapeutics market accounted for $2,334.5 million in 2018, and is expected to reach $3,528.8 million by 2026, registering a CAGR of 5.3% from 2019 to 2026.

Acute lymphocytic/lymphoblastic leukemia (ALL) is a type of cancer that develops from immature lymphocytes. “Acute” here indicates leukemia that quickly progresses and spreads across the body. ALL develops in bone marrow and quickly invades other parts of the body including the liver, spleen, lymph nodes, liver, central nervous system, spleen, central nervous system, and the blood. Symptoms can be non-specific and may include feeling weak and tired, paler skin, bruises, frequent and severe bleeding gums, nose bleeds; weight loss, shortness of breath, and loss of appetite. Various types of therapeutics are used for ALL treatment. Chemotherapy is one of the major therapeutics used for ALL treatment.

The market is experiencing growth owing to rise in incidences of acute lymphoblastic leukemia and the number of bone marrow biopsies across the world. In addition, the increase in investment in the R&D of different leukemia and rise in awareness of targeted therapies amongst the population further drive the growth of the ALL therapeutics market. Despite these, the stringent regulatory approvals for the therapeutics and the adverse side effects of the drugs used in the therapy impede the growth of the market worldwide. Also, patent expiry of the blockbuster drugs used in the treatment and the higher costs involved in the therapies limit the growth of the global ALL therapeutics market. Nonetheless, the rise in number of clinical trials and new product approvals are anticipated to create newer opportunities in the emerging as well as the developed markets.

Acute Lymphocytic/lymphoblastic Leukemia Therapeutics Market Segmentation

The acute lymphocytic/lymphoblastic leukemia therapeutics market is segmented based on drug, type, and region to provide a detailed assessment of the market. Based on drug, the market is divided into Hyper-CVAD Regimen, Linker Regimen, Nucleoside Metabolic Inhibitors (Clolar and Nelarabine), Targeted Drugs & Immunotherapy, CALGB 8811 Regimen, and Oncaspar. Based on type, it is classified into pediatrics and adults. Based on region, the acute lymphocytic/lymphoblastic leukemia therapeutics market size is analyzed across North America, Europe, Asia-Pacific, and LAMEA.

Acute Lymphocytic/Lymphoblastic Leukemia (ALL) Therapeutics Market

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Segment review

Based on drug, the market is divided into Hyper-CVAD Regimen, Linker Regimen, Nucleoside Metabolic Inhibitors (Clolar and Nelarabine), Targeted Drugs & Immunotherapy, CALGB 8811 Regimen, and Oncaspar. The Hyper-CVAD Regimen acquired the largest acute lymphocytic/lymphoblastic leukemia therapeutics market share in 2018 owing to wide usage in the ALL treatment. Hyper-CVAD Regimen is considered as one of the most commonly used therapy options for acute lymphocytic/lymphoblastic leukemia.

Furthermore, targeted drugs & immunotherapy are projected to grow at the fastest rate during the forecast period as these drugs have shown potential in the treatment of relapsed acute lymphocytic leukemia and is widely used in patients who do not respond to chemotherapy. Therefore, these factors contribute toward the growth of the ALL therapeutics market.

Acute Lymphocytic/Lymphoblastic Leukemia (ALL) Therapeutics Market  by Drugs

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According to type, the pediatrics segment generated the highest revenue in 2018 and is expected to maintain its dominance throughout the forecast period. This is attributed to the high incidences of acute lymphocytic/lymphoblastic leukemia among pediatric population. Acute lymphocytic/lymphoblastic leukemia is considered as one of the most common cancer types in pediatric population. Moreover, pediatric population have higher success rate for acute lymphocytic/lymphoblastic leukemia treatments.

Acute Lymphocytic/Lymphoblastic Leukemia (ALL) Therapeutics Market  by Type

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North America occupied the largest share of the market in 2018 and is expected to maintain its dominance during the forecast period owing to easy availability of treatments, high cost of treatments, and presence of majority of key players. However, Asia-Pacific is expected to witness the highest growth rate throughout the forecast period, due to its high population base and rise in patient awareness toward cancer care.

Acute Lymphocytic/Lymphoblastic Leukemia (ALL) Therapeutics Market by Region

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The major companies profiled in this report include Amgen, Inc., Bristol-Myers Squibb Company, Erytech Pharma, Leadiant Biosciences, Inc. (Sigma-Tau Pharmaceuticals Inc.), Novartis AG, Pfizer, Inc., Rare Disease Therapeutics, Inc., Sanofi, Spectrum Pharmaceuticals, Inc., and Takeda Pharmaceutical Company Limited.

Key Market Benefits for Acute Lymphocytic/lymphoblastic Leukemia Therapeutics Market:

  • This report entails a detailed quantitative analysis along with the current acute lymphocytic/lymphoblastic leukemia therapeutics market trends from 2018 to 2026 to identify the prevailing opportunities along with the strategic assessment of the global acute lymphocytic/lymphoblastic leukemia therapeutics market growth.
  • The market forecast is studied from 2019 to 2026.
  • The market size and estimations are based on a comprehensive analysis of key developments in the acute lymphocytic/lymphoblastic leukemia therapeutics industry.
  • A qualitative analysis based on innovative products facilitates strategic business planning.
  • The development strategies adopted by the key market players are enlisted to understand the competitive scenario of the market

Acute Lymphocytic/lymphoblastic Leukemia Therapeutics Key Market Segments:

By Type

  • Pediatrics
  • Adults

By Drug

  • Hyper-CVAD Regimen
  • Linker Regimen
  • Nucleoside Metabolic Inhibitors (Clolar and Nelarabine)
  • Targeted Drugs & Immunotherapy
  • CALGB 8811 Regimen
  • Oncaspar

By Region

  • North America
  • Europe
  • Asia-Pacific
  • LAMEA
 

CHAPTER 1:    INTRODUCTION

1.1.    Report description
1.2.    Key benefits to Stakeholders
1.3.    Key market segments
1.4.    Research methodology

1.4.1.    Secondary research
1.4.2.    Primary research
1.4.3.    Analyst tools and models

CHAPTER 2:    EXECUTIVE SUMMARY

2.1.    Key findings of the study
2.2.    CXO perspective

CHAPTER 3:    MARKET OVERVIEW

3.1.    Market definition and scope
3.2.    Key findings

3.2.1.    Top investment pockets
3.2.2.    Top winning strategies

3.3.    Porters five forces analysis

3.3.1.    Bargaining power of suppliers
3.3.2.    Threat of new entrants
3.3.3.    Threat of substitutes
3.3.4.    Competitive rivalry
3.3.5.    Bargaining power among buyers

3.4.    Market dynamics

3.4.1.    Drivers

3.4.1.1.    Rise in the Incidences of Acute Lymphoblastic Leukemia
3.4.1.2.    Rise in Number of New Product Approvals

3.4.2.    Restraints

3.4.2.1.    Patent Expiry of Blockbuster Drugs
3.4.2.2.    Side effects of the treatment

3.4.3.    Opportunity

3.4.3.1.    Increase in number of Clinical Trials

CHAPTER 4:    ACUTE LYMPHOCYTIC LEUKEMIA MARKET, BY TYPE

4.1.    Overview

4.1.1.    Market size and forecast

4.2.    Pediatric

4.2.1.    Market size and forecast

4.3.    Adult

4.3.1.    Market size and forecast

CHAPTER 5:    ACUTE LYMPHOCYTIC LEUKEMIA THERAPEUTICS MARKET, BY DRUG

5.1.    Overvie

5.1.1.    Market size and forecast

5.2.    Hyper-CVAD regimen

5.2.1.    Market size and forecast

5.3.    Linker regimen

5.3.1.    Market size and forecast

5.4.    Nucleoside metabolic inhibitors (Clolar and Nelarabine)

5.4.1.    Market size and forecast

5.5.    Targeted drugs & immunotherapy

5.5.1.    Market size and forecast

5.6.    CALGB 8811 regimen

5.6.1.    Market size and forecast

5.7.    Oncaspar

5.7.1.    Market size and forecast

CHAPTER 6:    ACUTE LYMPHOCYTIC/LYMPHOBLASTIC LEUKEMIA THERAPEUTICS MARKET, BY REGION

6.1.    Overview

6.1.1.    Market size and forecast

6.2.    North America

6.2.1.    Key market trends and opportunities

6.3.    Europe

6.3.1.    Key market trends and opportunities

6.4.    Asia-Pacific

6.4.1.    Key market trends and opportunities

6.5.    LAMEA

6.5.1.    Key market trends and opportunities

CHAPTER 7:    COMPANY PROFILES

7.1.    AMGEN, INC

7.1.1.    Company overview
7.1.2.    Company snapshot
7.1.3.    Operating business segments
7.1.4.    Product portfolio
7.1.5.    Business performance
7.1.6.    Key strategic moves and developments

7.2.    BRISTOL-MYERS SQUIBB COMPANY

7.2.1.    Company overview
7.2.2.    Company snapshot
7.2.3.    Operating business segments
7.2.4.    Product portfolio
7.2.5.    Business performance
7.2.6.    Key strategic moves and developments

7.3.    ERYTECH PHARMA

7.3.1.    Company overview
7.3.2.    Operating business segments
7.3.3.    Product portfolio
7.3.4.    Key strategic moves and developments

7.4.    LEADIANT BIOSCIENCES, INC. (SIGMA-TAU PHARMACEUTICALS INC.)

7.4.1.    Company overview
7.4.2.    Company snapshot
7.4.3.    Operating business segments
7.4.4.    Product portfolio

7.5.    NOVARTIS AG

7.5.1.    Company overview
7.5.2.    Company snapshot
7.5.3.    Operating business segments
7.5.4.    Product portfolio
7.5.5.    Business performance
7.5.6.    Key strategic moves and developments

7.6.    PFIZER, INC

7.6.1.    Company overview
7.6.2.    Company snapshot
7.6.3.    Operating business segments
7.6.4.    Product portfolio
7.6.5.    Business performance
7.6.6.    Key strategic moves and developments

7.7.    RARE DISEASE THERAPEUTICS, INC.

7.7.1.    Company overview
7.7.2.    Company snapshot
7.7.3.    Operating business segments
7.7.4.    Product portfolio

7.8.    SANOFI

7.8.1.    Company overview
7.8.2.    Operating business segments
7.8.3.    Product portfolio
7.8.4.    Business performance

7.9.    SPECTRUM PHARMACEUTICALS, INC

7.9.1.    Company overview
7.9.2.    Company snapshot
7.9.3.    Operating business segments
7.9.4.    Product portfolio
7.9.5.    Business performance
7.9.6.    Key strategic moves and developments

7.10.    TAKEDA PHARMACEUTICAL COMPANY LIMITED

7.10.1.    Company overview
7.10.2.    Operating business segments
7.10.3.    Product portfolio
7.10.4.    Key strategic moves and developments

LIST OF TABLES

TABLE 01.    ACUTE LYMPHOCYTIC LEUKEMIA MARKET, BY TYPE, 2018–2026 ($MILLION)
TABLE 02.    ACUTE LYMPHOCYTIC LEUKEMIA MARKET FOR PEDIATRIC, BY REGION, 2018–2026 ($MILLION)
TABLE 03.    ACUTE LYMPHOCYTIC LEUKEMIA MARKET FOR ADULTS, BY REGION, 2018–2026 ($MILLION)
TABLE 04.    ACUTE LYMPHOCYTIC/LYMPHOBLASTIC LEUKEMIA THERAPEUTICS MARKET, BY DRUGS, 2018–2026 ($MILLION)
TABLE 05.    ACUTE LYMPHOCYTIC LEUKEMIA THERAPEUTICS MARKET FOR HYPER-CVAD, BY REGION, 2018–2026 ($MILLION)
TABLE 06.    ACUTE LYMPHOCYTIC LEUKEMIA THERAPEUTICS MARKET FOR LINKER REGIMEN, BY REGION, 2018–2026 ($MILLION)
TABLE 07.    ACUTE LYMPHOCYTIC LEUKEMIA THERAPEUTICS MARKET FOR NUCLEOSIDE METABOLIC INHIBITORS, BY REGION,  2018–2026 ($MILLION)
TABLE 08.    ACUTE LYMPHOCYTIC LEUKEMIA THERAPEUTICS MARKET FOR LINKER REGIMEN, BY REGION, 2018–2026 ($MILLION)
TABLE 09.    ACUTE LYMPHOCYTIC LEUKEMIA THERAPEUTICS MARKET FOR CALGB 8811 REGIMEN, BY REGION, 2018–2026 ($MILLION)
TABLE 10.    ACUTE LYMPHOCYTIC LEUKEMIA THERAPEUTICS MARKET FOR LINKER REGIMEN, BY REGION, 2018–2026 ($MILLION)
TABLE 11.    ACUTE LYMPHOCYTIC LEUKEMIA THERAPEUTICS PRODUCT PIPELINE
TABLE 12.    GLOBAL ACUTE LYMPHOCYTIC/LYMPHOBLASTIC LEUKEMIA THERAPEUTICS MARKET ($MILLION)
TABLE 13.    NORTH AMERICA ACUTE LYMPHOCYTIC/LYMPHOBLASTIC LEUKEMIA THERAPEUTICS MARKET, BY TYPE, VALUE  (USD MILLION)
TABLE 14.    NORTH AMERICA ACUTE LYMPHOCYTIC/LYMPHOBLASTIC LEUKEMIA THERAPEUTICS MARKET, BY DRUGS, VALUE  (USD MILLION)
TABLE 15.    EUROPE ACUTE LYMPHOCYTIC/LYMPHOBLASTIC LEUKEMIA THERAPEUTICS MARKET, BY TYPE, VALUE (USD MILLION)
TABLE 16.    EUROPE ACUTE LYMPHOCYTIC/LYMPHOBLASTIC LEUKEMIA THERAPEUTICS MARKET, BY DRUGS, VALUE (USD MILLION)
TABLE 17.    ASIA-PACIFIC ACUTE LYMPHOCYTIC/LYMPHOBLASTIC LEUKEMIA THERAPEUTICS MARKET, BY TYPE, VALUE (USD MILLION)
TABLE 18.    ASIA-PACIFIC ACUTE LYMPHOCYTIC/LYMPHOBLASTIC LEUKEMIA THERAPEUTICS MARKET, BY DRUGS, VALUE  (USD MILLION)
TABLE 19.    LAMEA ACUTE LYMPHOCYTIC/LYMPHOBLASTIC LEUKEMIA THERAPEUTICS MARKET, BY TYPE, VALUE (USD MILLION)
TABLE 20.    LAMEA ACUTE LYMPHOCYTIC/LYMPHOBLASTIC LEUKEMIA THERAPEUTICS MARKET, BY DRUGS, VALUE (USD MILLION)
TABLE 21.    AMGEN INC.: COMPANY SNAPSHOT
TABLE 22.    AMGEN INC.: OPERATING SEGMENT
TABLE 23.    AMGEN INC.: PRODUCT PORTFOLIO
TABLE 24.    BRISTOL-MYERS SQUIBB COMPANY: COMPANY SNAPSHOT
TABLE 25.    BRISTOL-MYERS SQUIBB COMPANY: PRODUCT SEGMENTS
TABLE 26.    BECTON DICKINSON COMPANY: PRODUCT PORTFOLIO
TABLE 27.    ERYTECH PHARMA: COMPANY SNAPSHOT
TABLE 28.    ERYTECH PHARMA: OPERATING SEGMENTS
TABLE 29.    ERYTECH PHARMA: PRODUCT PORTFOLIO
TABLE 30.    LEADIANT BIOSCIENCES, INC. (SIGMA-TAU PHARMACEUTICALS INC.): COMPANY SNAPSHOT
TABLE 31.    LEADIANT BIOSCIENCES, INC. (SIGMA-TAU PHARMACEUTICALS INC.): OPERATING SEGMENTS
TABLE 32.    LEADIANT BIOSCIENCES, INC. (SIGMA-TAU PHARMACEUTICALS INC.): PRODUCT PORTFOLIO
TABLE 33.    NOVARTIS AG: COMPANY SNAPSHOT
TABLE 34.    NOVARTIS AG: OPERATING SEGMENTS
TABLE 35.    NOVARTIS AG: PRODUCT PORTFOLIO
TABLE 36.    PFIZER, INC: COMPANY SNAPSHOT
TABLE 37.    PFIZER, INC: OPERATING SEGMENTS
TABLE 38.    PFIZER, INC: PRODUCT PORTFOLIO
TABLE 39.    RARE DISEASE THERAPEUTICS, INC.: COMPANY SNAPSHOT
TABLE 40.    RARE DISEASE THERAPEUTICS, INC.: OPERATING SEGMENT
TABLE 41.    RARE DISEASE THERAPEUTICS, INC.: PRODUCT PORTFOLIO
TABLE 42.    SANOFI: COMPANY SNAPSHOT
TABLE 43.    SANOFI: OPERATING SEGMENTS
TABLE 44.    SANOFI: PRODUCT PORTFOLIO
TABLE 45.    SPECTRUM PHARMACEUTICALS, INC: COMPANY SNAPSHOT
TABLE 46.    SPECTRUM PHARMACEUTICALS, INC.: OPERATING SEGMENT
TABLE 47.    SPECTRUM PHARMACEUTICALS, INC.: PRODUCT PORTFOLIO
TABLE 48.    TAKEDA PHARMACEUTICAL COMPANY LIMITED: COMPANY SNAPSHOT
TABLE 49.    TAKEDA PHARMACEUTICAL COMPANY LIMITED: OPERATING SEGMENTS
TABLE 50.    TAKEDA PHARMACEUTICAL COMPANY LIMITED: PRODUCT PORTFOLIO

LIST OF FIGURES

FIGURE 01.    ACUTE LYMPHOCYTIC/LYMPHOBLASTIC LEUKEMIA THERAPEUTICS MARKET SEGMENTATION
FIGURE 02.    TOP WINNING STRATEGIES, BY YEAR, 2017-2019*
FIGURE 03.    TOP WINNING STRATEGIES, BY DEVELOPMENT, 2017-2019* (%)
FIGURE 04.    TOP WINNING STRATEGIES, BY COMPANY, 2017-2019*
FIGURE 05.    BARGAINING POWER OF SUPPLIERS
FIGURE 06.    THREAT OF NEW ENTRANTS
FIGURE 07.    THREAT OF SUBSTITUTES
FIGURE 08.    COMPETITIVE RIVALRY
FIGURE 09.    BARGAINING POWER AMONG BUYERS
FIGURE 10.    TOP IMPACTING FACTORS
FIGURE 11.    AMGEN INC.: NET SALES, 2016–2018 ($MILLION)
FIGURE 12.    AMGEN INC.: REVENUE SHARE BY SEGMENT, 2018 (%)
FIGURE 13.    AMGEN INC.: REVENUE SHARE BY REGION, 2018(%)
FIGURE 14.    BRISTOL-MYERS SQUIBB COMPANY: NET SALES, 2016–2018 ($MILLION)
FIGURE 15.    BRISTOL-MYERS SQUIBB COMPANY: REVENUE SHARE BY SEGMENT, 2018 (%)
FIGURE 16.    BRISTOL-MYERS SQUIBB COMPANY: REVENUE SHARE BY REGION, 2018(%)
FIGURE 17.    NOVARTIS AG: NET SALES, 2016–2018 ($MILLION)
FIGURE 18.    NOVARTIS AG: REVENUE SHARE BY SEGMENT, 2018 (%)
FIGURE 19.    NOVARTIS AG: REVENUE SHARE BY REGION, 2018(%)
FIGURE 20.    PFIZER, INC: NET SALES, 2016–2018 ($MILLION
FIGURE 21.    PFIZER, INC: REVENUE SHARE BY SEGMENT/TECHNOLOGY, 2018 (%)
FIGURE 22.    PFIZER, INC: REVENUE SHARE BY REGION, 2018 (%)
FIGURE 23.    SANOFI: NET SALES, 2016–2018 ($MILLION)
FIGURE 24.    SANOFI: REVENUE SHARE BY SEGMENT, 2018 (%
FIGURE 25.    SANOFI: REVENUE SHARE BY REGION, 2018(%)
FIGURE 26.    SPECTRUM PHARMACEUTICALS, INC: NET SALES, 2016–2018 ($MILLION)
FIGURE 27.    SPECTRUM PHARMACEUTICALS, INC.: REVENUE SHARE BY SEGMENT, 2018 (%)
FIGURE 28.    SPECTRUM PHARMACEUTICALS, INC.: REVENUE SHARE BY REGION, 2018(%)
FIGURE 29.    TAKEDA PHARMACEUTICAL COMPANY LIMITED: NET SALES, 2016–2018 ($MILLION)
FIGURE 30.    TAKEDA PHARMACEUTICAL COMPANY LIMITED: REVENUE SHARE BY REGION, 2018(%)

 
 

Acute lymphocytic/lymphoblastic leukemia therapeutics (ALL) is one of the most common acute leukemia in children and adults. Newer lab techniques and targeted therapy drugs against ALL are now being developed. The targeted therapy drugs are now becoming an important part in the ALL therapeutics market as they work differently from standard chemotherapy drugs by targeting specific gene inside normal bone marrow cells. Asia-Pacific is projected to register highest growth rate in the global acute lymphocytic/lymphoblastic leukemia therapeutics market due to massive increase in population, high prevalence of lymphoblastic leukemia, and rise in the healthcare market.

Rise in incidence rates and increase in prevalence rates of lymphoblastic leukemia, implementation of national screening programs, and support in reimbursement for ALL therapeutics are the major factors that drive the growth of the market. However, high costs associated with the treatment for cancer refrain patients from diagnosis and treatment. Moreover, side effects of the drugs used in the therapies significantly limits the diagnosis of lymphoblastic leukemia. Such factors are expected to restrain the market growth.

 

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