Oligonucleotides are short fragments of nucleic acids that are synthesized using enzyme chemistry and genetic engineering. Oligonucleotide synthesis and recombinant DNA techniques provide an opportunity to construct genes for proteins that are not available in nature. Oligonucleotides are used in laboratories for therapeutic, diagnostics, academic, and industrial procedures. They are also used for screening and initial research for target validation and drug production. Oligonucleotides synthesis occurs commercially to provide services for end-users as well as for individual use such as DNA synthesizing. Recently, successive improvements in oligonucleotide synthesis, automation, and amplification have brought about drastic changes in biological research. Nowadays, we can also make customizations and achieve the required sequence online easily whenever needed. These services vary extensively by the cost of per base pair, lengths, error rates, and throughput. Furthermore, X-ray and NMR help a lot to see 3D protein structures during the process. The strategic aim of oligonucleotides synthesis is to create proteins with prearranged structures and functions. The future role of oligonucleotides synthesis is to manufacture new drugs and catalysts.

Market scope and structure analysis:

COVID-19 scenario analysis:

• To take care of the infected population the demand for medical supplies is increasing. Respiratory support devices, such as atomizer, life-support machine, oxygen generator, and monitor, are among the majorly used medical devices in primary clinical treatment. Moreover, COVID-19 has led to a huge surge in demand for medical supplies such as personal protective equipment, including masks, gloves, and protective eyeglasses. 
• With rise in the number of COVID-19 cases worldwide, the need for medical supplies keeps on rising both from healthcare professionals and civil populations for precautionary measures. 
• Manufacturers of these products have a chance to capitalize on this increased demand for medical supplies to ensure adequate and continuous supply of personal protective equipment in the market.
• Attributed to such factors, COVID 19 is expected to have a significant impact on the oligonucleotide synthesis market.

Top impacting factors: Market scenario analysis, trends, drivers and impact analysis

Increase in research activities in the pharma and biotech sectors, oligonucleotide-based drugs, and the inundation of new customers in oligo-drug development arena rise the demand for innovative diagnostic therapeutic techniques. These are the major factors influencing the growth of the oligonucleotide synthesis market. Increase in adoption of synthesized oligonucleotide in clinical as well as diagnostic applications, rise in the expenditure of R&D field, investment of government bodies in various pharmaceutical and biotechnology research, plunging sequencing cost, and increase in public as well as private investment on genomics, and rise in venture capital investments positively affect the growth of the oligonucleotide market. In the past few years, the market has observed remarkable rise in the accretion of various small-scale oligonucleotide synthesis companies by big sharks to broaden their service offerings and products to expand their presence in the oligonucleotide synthesis market.

Additionally, the decline in cost of sequencing has resulted in hiked up demand for custom-made nucleotides for the desired sequence across various applications such as genetic testing, research, drug development, and forensics. This has encouraged the demand for oligonucleotide synthesis across various pharmaceutical and biotechnology industries.

On the other hand, there is limited number of market players existing in particular regions and lack of skilled personals in this field. These factors may hamper the growth of the oligonucleotide synthesis market.

New product launches to boost the market

On 26 February 2019, Thermo Fisher Scientific entered into collaboration with BioNTech. This collaboration helped BioNTech's messenger RNA manufacturing platform provide support to Thermo Fisher for supply of nucleotides, enzymes, and other critical raw materials. On 18 February 2019, Integrated DNA Technologies (IDT) broadened its courier zones of free next-day delivery service to various scientists based in Cambridge, Oxford, and London Universities. This service expansion helped IDT increase its customer base and also enable projects to pick up the pace. On March 9 2018, IDT was acquired by Danaher, which helped Danaher’s Life Sciences to expand its customer base.

Surge in usage in hospital applications

Hospitals account for the highest revenue generation for the oligonucleotide synthesis market. This is attributed to the remarkable number of inpatient & outpatient visits in hospitals combined with the high requirement of oligonucleotide drugs to accommodate the demand from the vast patient pool suffering from diseases such as spinal muscular atrophy, Duchenne muscular dystrophy, and other hepatic venous-occlusive diseases.
 

Key benefits of the report:

• This study presents the analytical depiction of the oligonucleotide synthesis market along with the current trends and future estimations to determine the imminent investment pockets.
• The report presents information related to key drivers, restraints, and opportunities along with a detailed analysis of the oligonucleotide synthesis market share.
• The current market is quantitatively analyzed from 2020 to 2027 to highlight the oligonucleotide synthesis market growth scenario.
• Porter’s five forces analysis illustrates the potency of buyers & suppliers in the market.
• The report provides a detailed analysis based on competitive intensity and how the competition will take shape in the coming years.

Questions answered in the oligonucleotide synthesis market research report:

• Which are the leading market players active in the oligonucleotide synthesis market?
• What are the current trends that will influence the oligonucleotide synthesis market in the next few years?
• What are the driving factors, restraints, and opportunities of the oligonucleotide synthesis market?
• What are the projections for the future that would help in taking further strategic steps?